1. Metabolic Enzyme/Protease
  2. Tyrosinase
  3. 3-O-Ethyl-L-ascorbic acid

3-O-Ethyl-L-ascorbic acid, a stable vitamin C derivative, is a cosmetic tyrosinase tnhibitor with a whitening capacity. 3-O-Ethyl-L-ascorbic acid also has antioxidant abilities.

For research use only. We do not sell to patients.

3-O-Ethyl-L-ascorbic acid Chemical Structure

3-O-Ethyl-L-ascorbic acid Chemical Structure

CAS No. : 86404-04-8

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5 g USD 40 In-stock
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Description

3-O-Ethyl-L-ascorbic acid, a stable vitamin C derivative, is a cosmetic tyrosinase tnhibitor with a whitening capacity. 3-O-Ethyl-L-ascorbic acid also has antioxidant abilities[1][2].

Molecular Weight

204.18

Formula

C8H12O6

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H](CO)[C@](O1)([H])C(OCC)=C(O)C1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (489.76 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8976 mL 24.4882 mL 48.9764 mL
5 mM 0.9795 mL 4.8976 mL 9.7953 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (489.76 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.8976 mL 24.4882 mL 48.9764 mL 122.4410 mL
5 mM 0.9795 mL 4.8976 mL 9.7953 mL 24.4882 mL
10 mM 0.4898 mL 2.4488 mL 4.8976 mL 12.2441 mL
15 mM 0.3265 mL 1.6325 mL 3.2651 mL 8.1627 mL
20 mM 0.2449 mL 1.2244 mL 2.4488 mL 6.1220 mL
25 mM 0.1959 mL 0.9795 mL 1.9591 mL 4.8976 mL
30 mM 0.1633 mL 0.8163 mL 1.6325 mL 4.0814 mL
40 mM 0.1224 mL 0.6122 mL 1.2244 mL 3.0610 mL
50 mM 0.0980 mL 0.4898 mL 0.9795 mL 2.4488 mL
60 mM 0.0816 mL 0.4081 mL 0.8163 mL 2.0407 mL
80 mM 0.0612 mL 0.3061 mL 0.6122 mL 1.5305 mL
100 mM 0.0490 mL 0.2449 mL 0.4898 mL 1.2244 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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3-O-Ethyl-L-ascorbic acid Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
3-O-Ethyl-L-ascorbic acid
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HY-W003607
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