(3R)-3-Pyrrolidinemethanol

Cat. No.: HY-60263: FAQs
Data Sheet Handling Instructions

Molarity Calculator

(3R)-3-Pyrrolidinemethanol is a molecular building block and the linker of NRX-0492 (HY-153357).

For research use only. We do not sell to patients.

(3R)-3-Pyrrolidinemethanol Chemical Structure

CAS No. : 110013-18-8

Size	Price	Stock	Quantity
100 mg	USD 25	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 43	In-stock	Estimated Time of Arrival: December 31
500 mg	USD 65	In-stock	Estimated Time of Arrival: December 31
1 g	USD 95	In-stock	Estimated Time of Arrival: December 31
5 g		Get quote
10 g		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

(3R)-3-Pyrrolidinemethanol is a molecular building block and the linker of NRX-0492 (HY-153357).

Molecular Weight

101.15

Formula

C₅H₁₁NO

CAS No.

110013-18-8

SMILES

OC[C@H]1CNCC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 175 mg/mL (1730.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	9.8863 mL	49.4315 mL	98.8631 mL
5 mM	1.9773 mL	9.8863 mL	19.7726 mL
10 mM	0.9886 mL	4.9432 mL	9.8863 mL

View the Complete Stock Solution Preparation Table

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang D, et al. NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts. Blood. 2023 Mar 30;141(13):1584-1596. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	9.8863 mL	49.4315 mL	98.8631 mL	247.1577 mL
	5 mM	1.9773 mL	9.8863 mL	19.7726 mL	49.4315 mL
	10 mM	0.9886 mL	4.9432 mL	9.8863 mL	24.7158 mL
	15 mM	0.6591 mL	3.2954 mL	6.5909 mL	16.4772 mL
	20 mM	0.4943 mL	2.4716 mL	4.9432 mL	12.3579 mL
	25 mM	0.3955 mL	1.9773 mL	3.9545 mL	9.8863 mL
	30 mM	0.3295 mL	1.6477 mL	3.2954 mL	8.2386 mL
	40 mM	0.2472 mL	1.2358 mL	2.4716 mL	6.1789 mL
	50 mM	0.1977 mL	0.9886 mL	1.9773 mL	4.9432 mL
	60 mM	0.1648 mL	0.8239 mL	1.6477 mL	4.1193 mL
	80 mM	0.1236 mL	0.6179 mL	1.2358 mL	3.0895 mL
	100 mM	0.0989 mL	0.4943 mL	0.9886 mL	2.4716 mL