4,2′,4′,6′-Tetramethoxychalcone

Cat. No.: HY-N12549 Purity: 99.51%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

4,2′,4′,6′-Tetramethoxychalcone is a flavonoids that can be isolated from Gnaphalium affine.

For research use only. We do not sell to patients.

4,2′,4′,6′-Tetramethoxychalcone Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

4,2′,4′,6′-Tetramethoxychalcone is a flavonoids that can be isolated from Gnaphalium affine^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	46.6 μM Compound: 13b	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25629304]
HeLa	IC₅₀	19.6 μM Compound: 13b	Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25629304]
HepG2	IC₅₀	13.5 μM Compound: 13b	Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25629304]

Molecular Weight

328.36

Formula

C₁₉H₂₀O₅

CAS No.

94103-36-3

Appearance

Solid

Color

White to off-white

SMILES

COC(C=C1)=CC=C1/C=C/C(C2=C(C=C(C=C2OC)OC)OC)=O

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (152.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0454 mL	15.2272 mL	30.4544 mL
5 mM	0.6091 mL	3.0454 mL	6.0909 mL
10 mM	0.3045 mL	1.5227 mL	3.0454 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.51%

Select Batch:

Data Sheet (267 KB) SDS (252 KB)

COA (247 KB) HNMR (240 KB) LCMS (97 KB)

Handling Instructions (2659 KB)

References

[1]. Morimoto M, et al. Insect antifeedant flavonoids from Gnaphalium affine D. Don. J Agric Food Chem. 2000 May;48(5):1888-91. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0454 mL	15.2272 mL	30.4544 mL	76.1360 mL
	5 mM	0.6091 mL	3.0454 mL	6.0909 mL	15.2272 mL
	10 mM	0.3045 mL	1.5227 mL	3.0454 mL	7.6136 mL
	15 mM	0.2030 mL	1.0151 mL	2.0303 mL	5.0757 mL
	20 mM	0.1523 mL	0.7614 mL	1.5227 mL	3.8068 mL
	25 mM	0.1218 mL	0.6091 mL	1.2182 mL	3.0454 mL
	30 mM	0.1015 mL	0.5076 mL	1.0151 mL	2.5379 mL
	40 mM	0.0761 mL	0.3807 mL	0.7614 mL	1.9034 mL
	50 mM	0.0609 mL	0.3045 mL	0.6091 mL	1.5227 mL
	60 mM	0.0508 mL	0.2538 mL	0.5076 mL	1.2689 mL
	80 mM	0.0381 mL	0.1903 mL	0.3807 mL	0.9517 mL
	100 mM	0.0305 mL	0.1523 mL	0.3045 mL	0.7614 mL