4-Amino-tempo (Synonyms: 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl)

Cat. No.: HY-W002004 Purity: 99.35%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

4-Amino-TEMPO can be used as a spin label for detecting radicals and the damage caused by them. 4-Amino-TEMPO possesses superoxide dismutase-mimetic activity, enabling it to easily penetrate cells and protect them from oxidative damage induced by H₂O₂. Additionally, 4-Amino-TEMPO exhibits significant radiation protective properties, effectively safeguarding DNA from oxidative stress-induced damage caused by UV exposure due to its ability to maintain a positive charge. Furthermore, 4-Amino-TEMPO is a highly selective oxidation catalyst widely used in the research and development of various specialty chemicals, including fragrances, pesticides, and others .

For research use only. We do not sell to patients.

4-Amino-tempo Chemical Structure

CAS No. : 14691-88-4

Size	Price	Stock
10 g	USD 25	Ask For Quote & Lead Time
25 g	USD 50	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

Other Forms of 4-Amino-tempo:

4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-¹⁵N,d₇ Get quote
4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇ Get quote

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Purity & Documentation
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Description

Molecular Weight

171.26

Formula

C₉H₁₉N₂O

CAS No.

14691-88-4

Appearance

<37°C Solid,>39°C Liquid

Color

Brown to reddish brown

SMILES

CC1(C)N([O])C(C)(C)CC(N)C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 200 mg/mL (1167.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.8391 mL	29.1954 mL	58.3908 mL
5 mM	1.1678 mL	5.8391 mL	11.6782 mL
10 mM	0.5839 mL	2.9195 mL	5.8391 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.60%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (249 KB)

Handling Instructions (2659 KB)

References

[1]. Żamojć K, Zdrowowicz M, Hać A, et al. Dihydroxy-substituted coumarins as fluorescent probes for nanomolar-level detection of the 4-amino-TEMPO spin label[J]. International journal of molecular sciences, 2019, 20(15): 3802. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.8391 mL	29.1954 mL	58.3908 mL	145.9769 mL
	5 mM	1.1678 mL	5.8391 mL	11.6782 mL	29.1954 mL
	10 mM	0.5839 mL	2.9195 mL	5.8391 mL	14.5977 mL
	15 mM	0.3893 mL	1.9464 mL	3.8927 mL	9.7318 mL
	20 mM	0.2920 mL	1.4598 mL	2.9195 mL	7.2988 mL
	25 mM	0.2336 mL	1.1678 mL	2.3356 mL	5.8391 mL
	30 mM	0.1946 mL	0.9732 mL	1.9464 mL	4.8659 mL
	40 mM	0.1460 mL	0.7299 mL	1.4598 mL	3.6494 mL
	50 mM	0.1168 mL	0.5839 mL	1.1678 mL	2.9195 mL
	60 mM	0.0973 mL	0.4866 mL	0.9732 mL	2.4329 mL
	80 mM	0.0730 mL	0.3649 mL	0.7299 mL	1.8247 mL
	100 mM	0.0584 mL	0.2920 mL	0.5839 mL	1.4598 mL

4-Amino-tempo Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Amino-tempo14691-88-44-Amino-2,2,6,6-tetramethylpiperidine-1-oxylOtherssuperoxide dismutase-mimetic activityfree radical detectionoxidative damagefragrancespesticidesInhibitorinhibitorinhibit

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