2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. 4-(Ethoxymethyl)phenol

4-(Ethoxymethyl)phenol  (Synonyms: p-Hydroxybenzyl Et ether)

Cat. No.: HY-N1875 Purity: 98.02%
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4-(Ethoxymethyl)phenol (p-Hydroxybenzyl Et ether) is a potent antioxidant from Amburana cearensis leaf extract, with in vitro cytogenotoxic properties. Amburana cearensis leaves can be used foe the research of respiratory diseases and inflammations.

For research use only. We do not sell to patients.

4-(Ethoxymethyl)phenol Chemical Structure

4-(Ethoxymethyl)phenol Chemical Structure

CAS No. : 57726-26-8

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4-(Ethoxymethyl)phenol Related Antibodies

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

  • Biological Activity

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Description

4-(Ethoxymethyl)phenol (p-Hydroxybenzyl Et ether) is a potent antioxidant from Amburana cearensis leaf extract, with in vitro cytogenotoxic properties. Amburana cearensis leaves can be used foe the research of respiratory diseases and inflammations[1].

Cellular Effect
Cell Line Type Value Description References
Neutrophil IC50
> 10 μM
Compound: 41
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
[PMID: 27525452]
Neutrophil IC50
> 10 μM
Compound: 41
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
[PMID: 27525452]
Molecular Weight

152.19

Formula

C9H12O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=CC=C(COCC)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (821.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.5707 mL 32.8537 mL 65.7073 mL
5 mM 1.3141 mL 6.5707 mL 13.1415 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.5707 mL 32.8537 mL 65.7073 mL 164.2683 mL
5 mM 1.3141 mL 6.5707 mL 13.1415 mL 32.8537 mL
10 mM 0.6571 mL 3.2854 mL 6.5707 mL 16.4268 mL
15 mM 0.4380 mL 2.1902 mL 4.3805 mL 10.9512 mL
20 mM 0.3285 mL 1.6427 mL 3.2854 mL 8.2134 mL
25 mM 0.2628 mL 1.3141 mL 2.6283 mL 6.5707 mL
30 mM 0.2190 mL 1.0951 mL 2.1902 mL 5.4756 mL
40 mM 0.1643 mL 0.8213 mL 1.6427 mL 4.1067 mL
50 mM 0.1314 mL 0.6571 mL 1.3141 mL 3.2854 mL
60 mM 0.1095 mL 0.5476 mL 1.0951 mL 2.7378 mL
80 mM 0.0821 mL 0.4107 mL 0.8213 mL 2.0534 mL
100 mM 0.0657 mL 0.3285 mL 0.6571 mL 1.6427 mL
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4-(Ethoxymethyl)phenol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-(Ethoxymethyl)phenol57726-26-8p-Hydroxybenzyl Et etherEstrogen Receptor/ERRantioxidantcytogenotoxic propertiesrespiratory diseasesinflammationInhibitorinhibitorinhibit

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