4’-Hydroxy Flurbiprofen-d₃

Name: 4’-Hydroxy Flurbiprofen-d 3
Brand: MedChemExpress
SKU: HY-132436S
Rating: 5.0 (1 reviews)

Cat. No.: HY-132436S Purity: 99.02%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

4’-Hydroxy Flurbiprofen-d₃ is the deuterium labeled 4’-Hydroxy Flurbiprofen[1].

For research use only. We do not sell to patients.

4’-Hydroxy Flurbiprofen-d<sub>3</sub> Chemical Structure

4’-Hydroxy Flurbiprofen-d₃ Chemical Structure

CAS No. : 1189694-02-7

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	Get quote
50 mg	Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

4’-Hydroxy Flurbiprofen-d₃ is the deuterium labeled 4’-Hydroxy Flurbiprofen[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

263.28

Formula

C₁₅H₁₀D₃FO₃

CAS No.

1189694-02-7

Appearance

Solid

Color

White to off-white

SMILES

FC1=C(C=CC(C(C(O)=O)C([2H])([2H])[2H])=C1)C2=CC=C(O)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 10 mg/mL (37.98 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7982 mL	18.9912 mL	37.9824 mL
5 mM	0.7596 mL	3.7982 mL	7.5965 mL
10 mM	0.3798 mL	1.8991 mL	3.7982 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.02%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (248 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7982 mL	18.9912 mL	37.9824 mL	94.9559 mL
	5 mM	0.7596 mL	3.7982 mL	7.5965 mL	18.9912 mL
	10 mM	0.3798 mL	1.8991 mL	3.7982 mL	9.4956 mL
	15 mM	0.2532 mL	1.2661 mL	2.5322 mL	6.3304 mL
	20 mM	0.1899 mL	0.9496 mL	1.8991 mL	4.7478 mL
	25 mM	0.1519 mL	0.7596 mL	1.5193 mL	3.7982 mL
	30 mM	0.1266 mL	0.6330 mL	1.2661 mL	3.1652 mL