2. Cell Cycle/DNA Damage Epigenetics Anti-infection
  3. HDAC Virus Protease
  4. 4-Phenylbutyric acid-d11

4-Phenylbutyric acid-d11  (Synonyms: 4-PBA-d11; Benzenebutyric acid-d11)

Cat. No.: HY-A0281S Purity: 99.30%
SDS COA Handling Instructions

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4-Phenylbutyric acid-d11 is the deuterium labeled 4-Phenylbutyric acid. 4-Phenylbutyric acid (4-PBA) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research.

For research use only. We do not sell to patients.

4-Phenylbutyric acid-d<sub>11</sub> Chemical Structure

4-Phenylbutyric acid-d11 Chemical Structure

CAS No. : 358730-86-6

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50 mg USD 250 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 4-Phenylbutyric acid-d11:

4-Phenylbutyric acid-d11 Related Antibodies

Top Publications Citing Use of Products

View All HDAC Isoform Specific Products:

View All Isoforms
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Description

4-Phenylbutyric acid-d11 is the deuterium labeled 4-Phenylbutyric acid. 4-Phenylbutyric acid (4-PBA) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4-Phenylbutyric acid-d11 Related Antibodies
Molecular Weight

175.27

Formula

C10HD11O2
CAS No.
Unlabeled CAS

1821-12-1
Appearance

Solid

Color

White to off-white

SMILES

OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (570.55 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7055 mL 28.5274 mL 57.0548 mL
5 mM 1.1411 mL 5.7055 mL 11.4110 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.30%

SDS (251 KB)

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.7055 mL 28.5274 mL 57.0548 mL 142.6371 mL
5 mM 1.1411 mL 5.7055 mL 11.4110 mL 28.5274 mL
10 mM 0.5705 mL 2.8527 mL 5.7055 mL 14.2637 mL
15 mM 0.3804 mL 1.9018 mL 3.8037 mL 9.5091 mL
20 mM 0.2853 mL 1.4264 mL 2.8527 mL 7.1319 mL
25 mM 0.2282 mL 1.1411 mL 2.2822 mL 5.7055 mL
30 mM 0.1902 mL 0.9509 mL 1.9018 mL 4.7546 mL
40 mM 0.1426 mL 0.7132 mL 1.4264 mL 3.5659 mL
50 mM 0.1141 mL 0.5705 mL 1.1411 mL 2.8527 mL
60 mM 0.0951 mL 0.4755 mL 0.9509 mL 2.3773 mL
80 mM 0.0713 mL 0.3566 mL 0.7132 mL 1.7830 mL
100 mM 0.0571 mL 0.2853 mL 0.5705 mL 1.4264 mL
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4-Phenylbutyric acid-d11 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Phenylbutyric acid-d11358730-86-64-PBA-d11Benzenebutyric acid-d11HDACVirus ProteaseHistone deacetylasesInhibitorinhibitorinhibit

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