2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. 5,7,2',6'-Tetrahydroxyflavone

5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM.

For research use only. We do not sell to patients.

5,7,2',6'-Tetrahydroxyflavone Chemical Structure

5,7,2',6'-Tetrahydroxyflavone Chemical Structure

CAS No. : 82475-00-1

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Based on 1 publication(s) in Google Scholar

5,7,2',6'-Tetrahydroxyflavone Related Antibodies

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View All Cytochrome P450 Isoform Specific Products:

View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

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Description

5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM[1].

IC50 & Target[1]

CYP3A4

7.8 μM (IC50)

Molecular Weight

286.24

Formula

C15H10O6
CAS No.
SMILES

O=C1C=C(C2=C(O)C=CC=C2O)OC3=C1C(O)=CC(O)=C3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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5,7,2',6'-Tetrahydroxyflavone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5,7,2',6'-Tetrahydroxyflavone82475-00-1Cytochrome P450CYPsCYP3A4flavonoidhepatic testosterone 6β-hydroxylationInhibitorinhibitorinhibit

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