2. Others Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Cytoskeleton NF-κB
  3. Isotope-Labeled Compounds PPAR PAK NF-κB Endogenous Metabolite
  4. 5-Aminosalicylic Acid-d3 hydrochloride

5-Aminosalicylic Acid-d3 hydrochloride  (Synonyms: Mesalamine-d3 hydrochloride; 5-ASA-d3 hydrochloride; Mesalazine-d3 hydrochloride)

Cat. No.: HY-15027S Purity: 99.00%
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5-Aminosalicylic Acid-d3 (hydrochloride) is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) hydrochloride acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.

For research use only. We do not sell to patients.

5-Aminosalicylic Acid-d<sub>3</sub> hydrochloride Chemical Structure

5-Aminosalicylic Acid-d3 hydrochloride Chemical Structure

CAS No. : 1346601-18-0

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5 mg USD 1100 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 5-Aminosalicylic Acid-d3 hydrochloride:

5-Aminosalicylic Acid-d3 hydrochloride Related Antibodies

Top Publications Citing Use of Products

View All PPAR Isoform Specific Products:

View All Isoforms
PPARα PPARβ/δ PPARγ PPAR PPARδ

View All PAK Isoform Specific Products:

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PAK1 PAK2 PAK3 PAK4 PAK5 PAK6

View All NF-κB Isoform Specific Products:

View All Isoforms
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

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Description

5-Aminosalicylic Acid-d3 (hydrochloride) is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) hydrochloride acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5-Aminosalicylic Acid-d3 hydrochloride Related Antibodies
Molecular Weight

192.61

Formula

C7H5D3ClNO3
CAS No.
Unlabeled CAS

89-57-6
Appearance

Solid

Color

White to off-white

SMILES

OC(C1=C(C([2H])=C([2H])C(N)=C1[2H])O)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: 99.00%

COA (253 KB)

Handling Instructions (2659 KB)
References
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5-Aminosalicylic Acid-d3 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Aminosalicylic Acid-d31346601-18-0Mesalamine-d35-ASA-d3Mesalazine-d3Isotope-Labeled CompoundsPPARPAKNF-κBEndogenous MetabolitePeroxisome proliferator-activated receptorsp21 activated kinasesNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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