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  4. 5-Bromo-2'-deoxycytidine

5-Bromo-2'-deoxycytidine is a DNA photosensitizer. 5-Bromo-2'-deoxycytidine modifies the double-stranded DNA, and determinate the DNA damage 300 nm photon.

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5-Bromo-2'-deoxycytidine Chemical Structure

5-Bromo-2'-deoxycytidine Chemical Structure

CAS No. : 1022-79-3

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Based on 1 publication(s) in Google Scholar

5-Bromo-2'-deoxycytidine Related Antibodies

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Description

5-Bromo-2'-deoxycytidine is a DNA photosensitizer. 5-Bromo-2'-deoxycytidine modifies the double-stranded DNA, and determinate the DNA damage 300 nm photon[1].

Molecular Weight

306.11

Formula

C9H12BrN3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N=C(N)C(Br)=C1)N1[C@@H]2O[C@H](CO)[C@@H](O)C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 175 mg/mL (571.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2668 mL 16.3340 mL 32.6680 mL
5 mM 0.6534 mL 3.2668 mL 6.5336 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.18%

COA (253 KB) HNMR (244 KB) RP-HPLC (262 KB) LCMS (93 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2668 mL 16.3340 mL 32.6680 mL 81.6700 mL
5 mM 0.6534 mL 3.2668 mL 6.5336 mL 16.3340 mL
10 mM 0.3267 mL 1.6334 mL 3.2668 mL 8.1670 mL
15 mM 0.2178 mL 1.0889 mL 2.1779 mL 5.4447 mL
20 mM 0.1633 mL 0.8167 mL 1.6334 mL 4.0835 mL
25 mM 0.1307 mL 0.6534 mL 1.3067 mL 3.2668 mL
30 mM 0.1089 mL 0.5445 mL 1.0889 mL 2.7223 mL
40 mM 0.0817 mL 0.4083 mL 0.8167 mL 2.0417 mL
50 mM 0.0653 mL 0.3267 mL 0.6534 mL 1.6334 mL
60 mM 0.0544 mL 0.2722 mL 0.5445 mL 1.3612 mL
80 mM 0.0408 mL 0.2042 mL 0.4083 mL 1.0209 mL
100 mM 0.0327 mL 0.1633 mL 0.3267 mL 0.8167 mL
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5-Bromo-2'-deoxycytidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Bromo-2'-deoxycytidine1022-79-3Biochemical Assay ReagentsPhotosensitizerInhibitorinhibitorinhibit

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