5-Chloro-2-hydroxybenzoic acid (Synonyms: 5-Chlorosalicylic acid; 5-Chloro-2-hydroxybenzoic acid)

Cat. No.: HY-W016866 Purity: 98.74%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

5-Chloro-2-hydroxybenzoic acid (5-Chlorosalicylic acid; 5-Chloro-2-hydroxybenzoic acid) is a biological material or organic compound that can be used in life science research.

For research use only. We do not sell to patients.

5-Chloro-2-hydroxybenzoic acid Chemical Structure

CAS No. : 321-14-2

Size	Stock	Quantity
Free Sample (0.1 - 0.5 mg)	Apply Now
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
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Description

5-Chloro-2-hydroxybenzoic acid (5-Chlorosalicylic acid; 5-Chloro-2-hydroxybenzoic acid) is a biological material or organic compound that can be used in life science research^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	CC₅₀	> 40 μM Compound: 5Cl-SA	Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 27089213]

Molecular Weight

172.57

Formula

C₇H₅ClO₃

CAS No.

321-14-2

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=CC(Cl)=CC=C1O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 200 mg/mL (1158.97 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.7949 mL	28.9743 mL	57.9485 mL
5 mM	1.1590 mL	5.7949 mL	11.5897 mL
10 mM	0.5795 mL	2.8974 mL	5.7949 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.74%

Select Batch:

Data Sheet (272 KB) SDS (479 KB)

COA (249 KB) HNMR (82 KB) RP-HPLC (181 KB) LCMS (233 KB)

Handling Instructions (2659 KB)

References

[1]. 5-Chloro-2-hydroxybenzoic acid [Content Brief]

[2]. Nicolson GL, Singer SJ. Ferritin-conjugated plant agglutinins as specific saccharide stains for electron microscopy: application to saccharides bound to cell membranes. Proc Natl Acad Sci U S A. 1971 May;68(5):942-5. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.7949 mL	28.9743 mL	57.9485 mL	144.8713 mL
	5 mM	1.1590 mL	5.7949 mL	11.5897 mL	28.9743 mL
	10 mM	0.5795 mL	2.8974 mL	5.7949 mL	14.4871 mL
	15 mM	0.3863 mL	1.9316 mL	3.8632 mL	9.6581 mL
	20 mM	0.2897 mL	1.4487 mL	2.8974 mL	7.2436 mL
	25 mM	0.2318 mL	1.1590 mL	2.3179 mL	5.7949 mL
	30 mM	0.1932 mL	0.9658 mL	1.9316 mL	4.8290 mL
	40 mM	0.1449 mL	0.7244 mL	1.4487 mL	3.6218 mL
	50 mM	0.1159 mL	0.5795 mL	1.1590 mL	2.8974 mL
	60 mM	0.0966 mL	0.4829 mL	0.9658 mL	2.4145 mL
	80 mM	0.0724 mL	0.3622 mL	0.7244 mL	1.8109 mL
	100 mM	0.0579 mL	0.2897 mL	0.5795 mL	1.4487 mL

5-Chloro-2-hydroxybenzoic acid Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Chloro-2-hydroxybenzoic acid321-14-25-Chlorosalicylic acid 5-Chloro-2-hydroxybenzoic acidBiochemical Assay ReagentsInhibitorinhibitorinhibit

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5-Chloro-2-hydroxybenzoic acid (Synonyms: 5-Chlorosalicylic acid; 5-Chloro-2-hydroxybenzoic acid)

5-Chloro-2-hydroxybenzoic acid Related Antibodies

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