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  4. 5-Chlorouracil

5-Chlorouracil  (Synonyms: Fluorouracil impurity)

Cat. No.: HY-I0959 Purity: 99.89%
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5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

5-Chlorouracil Chemical Structure

5-Chlorouracil Chemical Structure

CAS No. : 1820-81-1

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Based on 1 publication(s) in Google Scholar

Other Forms of 5-Chlorouracil:

5-Chlorouracil Related Antibodies

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Description

5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

In Vitro

5-Chlorouracil is a chlorinated derivative of the pyrimidine nucleoside base uracil . In vivo, it is converted into chlorodeoxyuridine, which is mutagenic and genotoxic. Uracil is chlorinated at the 5 position in a cell-free myeloperoxidase, peroxide, and chloride system in which hypochlorous acid is formed.2 5-Chlorouracil has been found in human neutrophils stimulated with phorbol 12-myristate 13-acetate in vitro and in inflammatory human exudate isolated from sites of superficial infection. Levels of 5-chlorouracil are incre ased in exudate isolated from the site of inflammation in a rat model of carrageenan-induced inflammation and in patient-derived human atherosclerotic aortic tissue. References

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5-Chlorouracil Related Antibodies
Molecular Weight

146.53

Formula

C4H3ClN2O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1NC(C(Cl)=CN1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
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5-Chlorouracil Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Chlorouracil1820-81-1Fluorouracil impurityBiochemical Assay Reagentsbiochemical reagentbiological materialorganic compoundlife scienceInhibitorinhibitorinhibit

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