1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine

5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine 

Cat. No.: HY-154779
Handling Instructions

5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine Chemical Structure

5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine Chemical Structure

CAS No. : 910129-15-6

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Other Forms of 5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine:

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Description

5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
0.09 mg/mL
Compound: 4b
Cytotoxicity against human HeLa cells after 3 days MTT assay
Cytotoxicity against human HeLa cells after 3 days MTT assay
[PMID: 22796042]
MCF7 IC50
0.12 mg/mL
Compound: 4b
Cytotoxicity against human MCF7 cells after 3 days MTT assay
Cytotoxicity against human MCF7 cells after 3 days MTT assay
[PMID: 22796042]
NCI-H69 IC50
0.37 mg/mL
Compound: 4b
Cytotoxicity against human NCI-H69 cells after 3 days MTT assay
Cytotoxicity against human NCI-H69 cells after 3 days MTT assay
[PMID: 22796042]
Molecular Weight

359.35

Formula

C15H22FN3O6

CAS No.
SMILES

O=C1N=C(NC(OCC(C)CC)=O)C(F)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](C)O2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine
Cat. No.:
HY-154779
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