5'-Guanylic acid-¹⁵N₅,d₁₂ dilithium (Synonyms: 5'-GMP-¹⁵N₅,d₁₂ dilithium; 5'-guanosine monophosphate-¹⁵N₅,d₁₂ dilithium)

Cat. No.: HY-N5134S4: FAQs
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5'-Guanylic acid-¹⁵N₅,d₁₂ (5'-GMP-¹⁵N₅,d₁₂ dilithium; 5'-guanosine monophosphate-¹⁵N₅,d₁₂) dilithium is deuterium and ¹⁵N labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.

For research use only. We do not sell to patients.

5'-Guanylic acid-<sup>15</sup>N<sub>5</sub>,d<sub>12</sub> dilithium Chemical Structure

5'-Guanylic acid-¹⁵N₅,d₁₂ dilithium Chemical Structure

Size		Stock
1 mg		Get quote	Estimated Time of Arrival: December 31

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Other Forms of 5'-Guanylic acid-¹⁵N₅,d₁₂ dilithium:

5'-Guanylic acid Get quote
5'-Guanylic acid-13C5 Get quote
5'-Guanylic acid-¹³C₁₀ dilithium Get quote
5'-Guanylic acid-¹⁵N₅ dilithium Get quote
5'-Guanylic acid-d₁₂ dilithium Get quote

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Description	5'-Guanylic acid-¹⁵N₅,d₁₂ (5'-GMP-¹⁵N₅,d₁₂ dilithium; 5'-guanosine monophosphate-¹⁵N₅,d₁₂) dilithium is deuterium and ¹⁵N labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 5'-Guanylic acid-¹⁵N₅,d₁₂ dilithium Related Antibodies
Molecular Weight	392.13
Formula	C₁₀D₁₂Li₂¹⁵N₅O₈P
Unlabeled CAS	85-32-5
SMILES	O=P(O[Li])(O[Li])OC([2H])([2H])[C@@]1([2H])O[C@]([15N]2C([15N]=C([15N]([2H])[2H])[15N]([2H])C3=O)=C3[15N]=C2[2H])([2H])[C@](O[2H])([2H])[C@]1([2H])O[2H]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (272 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

5'-Guanylic acid-¹⁵N₅,d₁₂ dilithium Related Classifications

Metabolic Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5'-Guanylic acid-¹⁵N₅,d₁₂ dilithium5'-GMP-¹⁵N₅,d₁₂ dilithium5'-guanosine monophosphate-¹⁵N₅,d₁₂ dilithiumIsotope-Labeled CompoundsEndogenous MetaboliteInhibitorinhibitorinhibit

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5'-Guanylic acid-15N5,d12 dilithium (Synonyms: 5'-GMP-15N5,d12 dilithium; 5'-guanosine monophosphate-15N5,d12 dilithium)

Other Forms of 5'-Guanylic acid-15N5,d12 dilithium:

5'-Guanylic acid-15N5,d12 dilithium Related Antibodies

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•Related Small Molecules:

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