2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 5-Hydroxyindole-3-acetic acid-d2

5-Hydroxyindole-3-acetic acid-d2 

Cat. No.: HY-W008253S Purity: 99.00%
COA Handling Instructions

Molarity Calculator

5-Hydroxyindole-3-acetic acid-d2 is the deuterium labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.

For research use only. We do not sell to patients.

5-Hydroxyindole-3-acetic acid-d<sub>2</sub> Chemical Structure

5-Hydroxyindole-3-acetic acid-d2 Chemical Structure

CAS No. : 56209-31-5

Size Price Stock Quantity
5 mg USD 588 In-stock
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 5-Hydroxyindole-3-acetic acid-d2:

5-Hydroxyindole-3-acetic acid-d2 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

5-Hydroxyindole-3-acetic acid-d2 is the deuterium labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5-Hydroxyindole-3-acetic acid-d2 Related Antibodies
Molecular Weight

193.20

Formula

C10H7D2NO3
CAS No.
Unlabeled CAS

54-16-0
Appearance

Solid

Color

White to off-white

SMILES

OC(C([2H])([2H])C(C1=C2)=CNC1=CC=C2O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (517.60 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.1760 mL 25.8799 mL 51.7598 mL
5 mM 1.0352 mL 5.1760 mL 10.3520 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.00%

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.1760 mL 25.8799 mL 51.7598 mL 129.3996 mL
5 mM 1.0352 mL 5.1760 mL 10.3520 mL 25.8799 mL
10 mM 0.5176 mL 2.5880 mL 5.1760 mL 12.9400 mL
15 mM 0.3451 mL 1.7253 mL 3.4507 mL 8.6266 mL
20 mM 0.2588 mL 1.2940 mL 2.5880 mL 6.4700 mL
25 mM 0.2070 mL 1.0352 mL 2.0704 mL 5.1760 mL
30 mM 0.1725 mL 0.8627 mL 1.7253 mL 4.3133 mL
40 mM 0.1294 mL 0.6470 mL 1.2940 mL 3.2350 mL
50 mM 0.1035 mL 0.5176 mL 1.0352 mL 2.5880 mL
60 mM 0.0863 mL 0.4313 mL 0.8627 mL 2.1567 mL
80 mM 0.0647 mL 0.3235 mL 0.6470 mL 1.6175 mL
100 mM 0.0518 mL 0.2588 mL 0.5176 mL 1.2940 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

5-Hydroxyindole-3-acetic acid-d2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Hydroxyindole-3-acetic acid-d256209-31-5Endogenous MetaboliteInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
5-Hydroxyindole-3-acetic acid-d2
Cat. No.:
HY-W008253S
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.