1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 5-Iodo-cytidine

5-Iodo-cytidine  (Synonyms: 5-Iodo-D-cytidine)

Cat. No.: HY-W008615 Purity: 98.21%
COA Handling Instructions

5-Iodo-cytidine (5-Iodo-D-cytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

5-Iodo-cytidine Chemical Structure

5-Iodo-cytidine Chemical Structure

CAS No. : 1147-23-5

Size Price Stock
1 g USD 35 Ask For Quote & Lead Time
5 g USD 130 Ask For Quote & Lead Time

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Description

5-Iodo-cytidine (5-Iodo-D-cytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Molecular Weight

369.11

Formula

C9H12IN3O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N=C(N)C(I)=C1)N1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (270.92 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7092 mL 13.5461 mL 27.0922 mL
5 mM 0.5418 mL 2.7092 mL 5.4184 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.21%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7092 mL 13.5461 mL 27.0922 mL 67.7305 mL
5 mM 0.5418 mL 2.7092 mL 5.4184 mL 13.5461 mL
10 mM 0.2709 mL 1.3546 mL 2.7092 mL 6.7730 mL
15 mM 0.1806 mL 0.9031 mL 1.8061 mL 4.5154 mL
20 mM 0.1355 mL 0.6773 mL 1.3546 mL 3.3865 mL
25 mM 0.1084 mL 0.5418 mL 1.0837 mL 2.7092 mL
30 mM 0.0903 mL 0.4515 mL 0.9031 mL 2.2577 mL
40 mM 0.0677 mL 0.3387 mL 0.6773 mL 1.6933 mL
50 mM 0.0542 mL 0.2709 mL 0.5418 mL 1.3546 mL
60 mM 0.0452 mL 0.2258 mL 0.4515 mL 1.1288 mL
80 mM 0.0339 mL 0.1693 mL 0.3387 mL 0.8466 mL
100 mM 0.0271 mL 0.1355 mL 0.2709 mL 0.6773 mL
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5-Iodo-cytidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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5-Iodo-cytidine
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