5-Methoxyuridine 5'-triphosphate (trisodium) solution (100mM)

Cat. No.: HY-112581B Purity: 99.89%: FAQs
Data Sheet SDS COA Handling Instructions

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5-Methoxyuridine 5'-triphosphate trisodium solution (100mM) is a modified nucleotide triphosphate (NTP). 5-Methoxyuridine 5'-triphosphate trisodium can be added into mRNA with T7 RNA polymerase.

For research use only. We do not sell to patients.

5-Methoxyuridine 5'-triphosphate (trisodium) solution (100mM) Chemical Structure

Size	Price	Stock	Quantity
Solvent
58 mg (100 mM * 1 mL in Water)	USD 330	In-stock	Estimated Time of Arrival: December 31

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Description

5-Methoxyuridine 5'-triphosphate trisodium solution (100mM) is a modified nucleotide triphosphate (NTP). 5-Methoxyuridine 5'-triphosphate trisodium can be added into mRNA with T7 RNA polymerase^[1].

Molecular Weight

580.11

Formula

C₁₀H₁₄N₂Na₃O₁₆P₃

Appearance

Liquid

Color

Colorless to light yellow

SMILES

O[C@H]1[C@@](N2C=C(C(NC2=O)=O)OC)([H])O[C@@H]([C@H]1O)COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (172.38 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7238 mL	8.6191 mL	17.2381 mL
5 mM	0.3448 mL	1.7238 mL	3.4476 mL
10 mM	0.1724 mL	0.8619 mL	1.7238 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.89%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (253 KB) HNMR (287 KB) CNMR (299 KB) RP-HPLC (270 KB) MS (71 KB)

Handling Instructions (2659 KB)

References

[1]. Furtado D, et al. mRNA Treatment Rescues Niemann-Pick Disease Type C1 in Patient Fibroblasts. Mol Pharm. 2022 Sep 20. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.7238 mL	8.6191 mL	17.2381 mL	43.0953 mL
	5 mM	0.3448 mL	1.7238 mL	3.4476 mL	8.6191 mL
	10 mM	0.1724 mL	0.8619 mL	1.7238 mL	4.3095 mL
	15 mM	0.1149 mL	0.5746 mL	1.1492 mL	2.8730 mL
	20 mM	0.0862 mL	0.4310 mL	0.8619 mL	2.1548 mL
	25 mM	0.0690 mL	0.3448 mL	0.6895 mL	1.7238 mL
	30 mM	0.0575 mL	0.2873 mL	0.5746 mL	1.4365 mL
	40 mM	0.0431 mL	0.2155 mL	0.4310 mL	1.0774 mL
	50 mM	0.0345 mL	0.1724 mL	0.3448 mL	0.8619 mL
	60 mM	0.0287 mL	0.1437 mL	0.2873 mL	0.7183 mL
	80 mM	0.0215 mL	0.1077 mL	0.2155 mL	0.5387 mL
	100 mM	0.0172 mL	0.0862 mL	0.1724 mL	0.4310 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.