5'-Methylthioadenosine-¹³C₆ (Synonyms: 5'-(Methylthio)-5'-deoxyadenosine-¹³C₆; 5'-Deoxy-5'-(methylthio)adenosine-¹³C₆; 5'-S-Methyl-5'-thioadenosine-¹³C₆)

Name: 5'-Methylthioadenosine- 13 C 6
Brand: MedChemExpress
SKU: HY-16938S
Rating: 4.5 (1 reviews)

Cat. No.: HY-16938S Purity: 98.45%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

5'-Methylthioadenosine-¹³C₆ is the ¹³C-labeled 5'-Methylthioadenosine. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2].

For research use only. We do not sell to patients.

5'-Methylthioadenosine-<sup>13</sup>C<sub>6</sub> Chemical Structure

5'-Methylthioadenosine-¹³C₆ Chemical Structure

CAS No. : 2421187-73-5

Size	Price	Stock	Quantity
1 mg	USD 5700	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 5'-Methylthioadenosine-¹³C₆:

5'-Methylthioadenosine In-stock

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

303.29

Formula

C₅¹³C₆H₁₅N₅O₃S

CAS No.

2421187-73-5

Unlabeled CAS

2457-80-9

Appearance

Solid

Color

White to off-white

SMILES

O[13C@H]1[13C@@H](O)[13C@@]([H])(O[13C@@H]1[13CH2]S[13CH3])N2C=NC3=C2N=CN=C3N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: 98.45%

Select Batch:

Data Sheet (269 KB) SDS (394 KB)

COA (250 KB) RP-HPLC (221 KB) MS (90 KB)

Handling Instructions (2659 KB)

References

[1]. Yaofeng Li, et al. 5'-Methylthioadenosine and Cancer: old molecules, new understanding. J Cancer. 2019;10(4):927-936. [Content Brief]

[2]. Tang Y, et al. 5'-Methylthioadenosine attenuates ischemia reperfusion injury after liver transplantation in rats. Inflammation. 2014;37(5):1366-1373. [Content Brief]

[3]. Li Y, et al. 5'-Methylthioadenosine and Cancer: old molecules, new understanding. J Cancer. 2019;10(4):927-936.

[4]. Tang B, et al. Specific Targeting of MTAP-Deleted Tumors with a Combination of 2'-Fluoroadenine and 5'-Methylthioadenosine. Cancer Res. 2018;78(15):4386-4395. [Content Brief]

[5]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

5'-Methylthioadenosine-¹³C₆ Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5'-Methylthioadenosine-¹³C₆2421187-73-55'-(Methylthio)-5'-deoxyadenosine-¹³C₆5'-Deoxy-5'-(methylthio)adenosine-¹³C₆5'-S-Methyl-5'-thioadenosine-¹³C₆Endogenous MetaboliteApoptosisInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *

Organization Name *

Country or Region *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

5'-Methylthioadenosine-13C6 (Synonyms: 5'-(Methylthio)-5'-deoxyadenosine-13C6; 5'-Deoxy-5'-(methylthio)adenosine-13C6; 5'-S-Methyl-5'-thioadenosine-13C6)

Customer Review

Other Forms of 5'-Methylthioadenosine-13C6:

5'-Methylthioadenosine-13C6 Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

5'-Methylthioadenosine-13C6 Related Antibodies

5'-Methylthioadenosine-13C6 Related Classifications

Molarity Calculator

Dilution Calculator

The molarity calculator equation

The dilution calculator equation

Keywords:

Your Recently Viewed Products:

Customer Review

Request for HNMR Report

Request for HNMR Report

5'-Methylthioadenosine-¹³C₆ (Synonyms: 5'-(Methylthio)-5'-deoxyadenosine-¹³C₆; 5'-Deoxy-5'-(methylthio)adenosine-¹³C₆; 5'-S-Methyl-5'-thioadenosine-¹³C₆)

Other Forms of 5'-Methylthioadenosine-¹³C₆:

5'-Methylthioadenosine-¹³C₆ Related Antibodies

5'-Methylthioadenosine-¹³C₆ Related Antibodies

5'-Methylthioadenosine-¹³C₆ Related Classifications