5-O-Demethyl-28-hydroxy-Avermectin A1a

Cat. No.: HY-147001 Purity: ≥96.0%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

5-O-Demethyl-28-hydroxy-Avermectin A1a is a degradation product of Avermectin B1a (HY-15308).

For research use only. We do not sell to patients.

5-O-Demethyl-28-hydroxy-Avermectin A1a Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
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Description

5-O-Demethyl-28-hydroxy-Avermectin A1a is a degradation product of Avermectin B1a (HY-15308).

Molecular Weight

889.08

Formula

C₄₈H₇₂O₁₅

CAS No.

96722-46-2

Appearance

Solid

Color

White to off-white

SMILES

C[C@H]([C@@]1([H])O[C@]2(C=C[C@@H]1C)C[C@](OC([C@@](C=C3C)([H])[C@@]([C@]([C@@H]3O)([H])OC4O)(/C4=C/C=C/[C@@H]5C)O)=O)([H])C[C@](C/C=C([C@H]5O[C@H](O[C@H]6C)C[C@@H]([C@H]6O[C@H](O[C@H]7C)C[C@@H]([C@H]7O)OC)OC)\C)([H])O2)CC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL (56.24 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1248 mL	5.6238 mL	11.2476 mL
5 mM	0.2250 mL	1.1248 mL	2.2495 mL
10 mM	0.1125 mL	0.5624 mL	1.1248 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥96.0%

Select Batch:

Data Sheet (247 KB) SDS (251 KB)

COA (253 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1248 mL	5.6238 mL	11.2476 mL	28.1190 mL
	5 mM	0.2250 mL	1.1248 mL	2.2495 mL	5.6238 mL
	10 mM	0.1125 mL	0.5624 mL	1.1248 mL	2.8119 mL
	15 mM	0.0750 mL	0.3749 mL	0.7498 mL	1.8746 mL
	20 mM	0.0562 mL	0.2812 mL	0.5624 mL	1.4059 mL
	25 mM	0.0450 mL	0.2250 mL	0.4499 mL	1.1248 mL
	30 mM	0.0375 mL	0.1875 mL	0.3749 mL	0.9373 mL
	40 mM	0.0281 mL	0.1406 mL	0.2812 mL	0.7030 mL
	50 mM	0.0225 mL	0.1125 mL	0.2250 mL	0.5624 mL