2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 5'-ODMT cEt m5U Phosphoramidite (Amidite)

5'-ODMT cEt m5U Phosphoramidite (Amidite) 

Cat. No.: HY-148506 Purity: 99.25%
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5'-ODMT cEt m5U Phosphoramidite Amidite is a locked nucleic acid (LNA) analog. 5'-ODMT cEt m5U Phosphoramidite Amidite shows excellent safety and antisense activity.

For research use only. We do not sell to patients.

5'-ODMT cEt m5U Phosphoramidite (Amidite) Chemical Structure

5'-ODMT cEt m5U Phosphoramidite (Amidite) Chemical Structure

CAS No. : 1197033-22-9

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Based on 1 publication(s) in Google Scholar

5'-ODMT cEt m5U Phosphoramidite (Amidite) Related Antibodies

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Description

5'-ODMT cEt m5U Phosphoramidite Amidite is a locked nucleic acid (LNA) analog. 5'-ODMT cEt m5U Phosphoramidite Amidite shows excellent safety and antisense activity[1][2].

Molecular Weight

786.85

Formula

C42H51N4O9P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC1=CC=C(C(C2=CC=C(OC)C=C2)(OC[C@]3(O[C@H]4N5C=C(C)C(NC5=O)=O)[C@@H](O[C@@]4([C@@H]3OP(N(C(C)C)C(C)C)OCCC#N)[H])C)C6=CC=CC=C6)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (158.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2709 mL 6.3545 mL 12.7089 mL
5 mM 0.2542 mL 1.2709 mL 2.5418 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2709 mL 6.3545 mL 12.7089 mL 31.7723 mL
5 mM 0.2542 mL 1.2709 mL 2.5418 mL 6.3545 mL
10 mM 0.1271 mL 0.6354 mL 1.2709 mL 3.1772 mL
15 mM 0.0847 mL 0.4236 mL 0.8473 mL 2.1182 mL
20 mM 0.0635 mL 0.3177 mL 0.6354 mL 1.5886 mL
25 mM 0.0508 mL 0.2542 mL 0.5084 mL 1.2709 mL
30 mM 0.0424 mL 0.2118 mL 0.4236 mL 1.0591 mL
40 mM 0.0318 mL 0.1589 mL 0.3177 mL 0.7943 mL
50 mM 0.0254 mL 0.1271 mL 0.2542 mL 0.6354 mL
60 mM 0.0212 mL 0.1059 mL 0.2118 mL 0.5295 mL
80 mM 0.0159 mL 0.0794 mL 0.1589 mL 0.3972 mL
100 mM 0.0127 mL 0.0635 mL 0.1271 mL 0.3177 mL
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5'-ODMT cEt m5U Phosphoramidite (Amidite) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5'-ODMT cEt m5U Phosphoramidite (Amidite)1197033-22-9Nucleoside Antimetabolite/AnalogInhibitorinhibitorinhibit

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