2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. 5-Propargylamino-dCTP

5-Propargylamino-dCTP is a nucleoside molecule extracted from patent US9035035B2, compound dCTP-PA. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

5-Propargylamino-dCTP Chemical Structure

5-Propargylamino-dCTP Chemical Structure

CAS No. : 115899-39-3

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5 mg USD 200 In-stock
10 mg USD 320 In-stock
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Based on 1 publication(s) in Google Scholar

5-Propargylamino-dCTP Related Antibodies

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Description

5-Propargylamino-dCTP is a nucleoside molecule extracted from patent US9035035B2, compound dCTP-PA. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis[1]. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Molecular Weight

520.22

Formula

C12H19N4O13P3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=[P](O[P](O[P](O)(O)=O)(O)=O)(O)OC[C@@H](O1)[C@@H](O)C[C@@H]1N(C2=O)C=C(C(N)=N2)C#CCN
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (480.57 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9223 mL 9.6113 mL 19.2226 mL
5 mM 0.3845 mL 1.9223 mL 3.8445 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (248 KB) HNMR (272 KB) CNMR (329 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.9223 mL 9.6113 mL 19.2226 mL 48.0566 mL
5 mM 0.3845 mL 1.9223 mL 3.8445 mL 9.6113 mL
10 mM 0.1922 mL 0.9611 mL 1.9223 mL 4.8057 mL
15 mM 0.1282 mL 0.6408 mL 1.2815 mL 3.2038 mL
20 mM 0.0961 mL 0.4806 mL 0.9611 mL 2.4028 mL
25 mM 0.0769 mL 0.3845 mL 0.7689 mL 1.9223 mL
30 mM 0.0641 mL 0.3204 mL 0.6408 mL 1.6019 mL
40 mM 0.0481 mL 0.2403 mL 0.4806 mL 1.2014 mL
50 mM 0.0384 mL 0.1922 mL 0.3845 mL 0.9611 mL
60 mM 0.0320 mL 0.1602 mL 0.3204 mL 0.8009 mL
80 mM 0.0240 mL 0.1201 mL 0.2403 mL 0.6007 mL
100 mM 0.0192 mL 0.0961 mL 0.1922 mL 0.4806 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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5-Propargylamino-dCTP Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Propargylamino-dCTP115899-39-3DNA/RNA SynthesismodifiednucleotideDNAnucleicacidsequencinglabelingInhibitorinhibitorinhibit

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