2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. 6-Methoxy-2-naphthoic acid

6-Methoxy-2-naphthoic acid  (Synonyms: Naproxen impurity O)

Cat. No.: HY-B2121 Purity: ≥98.0%
COA Handling Instructions

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6-Methoxy-2-naphthoic acid is an NMDA receptor modulator extracted from patent WO 2012019106 A2.

For research use only. We do not sell to patients.

6-Methoxy-2-naphthoic acid Chemical Structure

6-Methoxy-2-naphthoic acid Chemical Structure

CAS No. : 2471-70-7

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10 mM * 1 mL in DMSO
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Other Forms of 6-Methoxy-2-naphthoic acid:

6-Methoxy-2-naphthoic acid Related Antibodies

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Description

6-Methoxy-2-naphthoic acid is an NMDA receptor modulator extracted from patent WO 2012019106 A2.

IC50 & Target

NMDA Receptor

 

Molecular Weight

202.21

Formula

C12H10O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C2C=C(OC)C=CC2=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 60 mg/mL (296.72 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9454 mL 24.7268 mL 49.4535 mL
5 mM 0.9891 mL 4.9454 mL 9.8907 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.73%

COA (246 KB) HNMR (117 KB) RP-HPLC (190 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.9454 mL 24.7268 mL 49.4535 mL 123.6338 mL
5 mM 0.9891 mL 4.9454 mL 9.8907 mL 24.7268 mL
10 mM 0.4945 mL 2.4727 mL 4.9454 mL 12.3634 mL
15 mM 0.3297 mL 1.6485 mL 3.2969 mL 8.2423 mL
20 mM 0.2473 mL 1.2363 mL 2.4727 mL 6.1817 mL
25 mM 0.1978 mL 0.9891 mL 1.9781 mL 4.9454 mL
30 mM 0.1648 mL 0.8242 mL 1.6485 mL 4.1211 mL
40 mM 0.1236 mL 0.6182 mL 1.2363 mL 3.0908 mL
50 mM 0.0989 mL 0.4945 mL 0.9891 mL 2.4727 mL
60 mM 0.0824 mL 0.4121 mL 0.8242 mL 2.0606 mL
80 mM 0.0618 mL 0.3091 mL 0.6182 mL 1.5454 mL
100 mM 0.0495 mL 0.2473 mL 0.4945 mL 1.2363 mL
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6-Methoxy-2-naphthoic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Methoxy-2-naphthoic acid2471-70-7Naproxen impurity OiGluRIonotropic glutamate receptorsInhibitorinhibitorinhibit

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