2. Others
  3. Isotope-Labeled Compounds
  4. 6-Aminocaproic acid-d6

6-Aminocaproic acid-d6  (Synonyms: EACA-d6; Epsilon-Amino-n-caproic acid-d6; 6-Aminohexanoic acid-d6)

Cat. No.: HY-B0236S Purity: ≥99.0%
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6-Aminocaproic acid-d6 is deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2].

For research use only. We do not sell to patients.

6-Aminocaproic acid-d<sub>6</sub> Chemical Structure

6-Aminocaproic acid-d6 Chemical Structure

CAS No. : 1228656-08-3

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Based on 1 publication(s) in Google Scholar

Other Forms of 6-Aminocaproic acid-d6:

6-Aminocaproic acid-d6 Related Antibodies

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Description

6-Aminocaproic acid-d6 is deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-Aminocaproic acid-d6 Related Antibodies
Molecular Weight

137.21

Formula

C6H7D6NO2
CAS No.
Unlabeled CAS

60-32-2
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CC([2H])([2H])C([2H])([2H])C([2H])([2H])CN
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (364.40 mM)

H2O : ≥ 50 mg/mL (364.40 mM)

DMSO : 1 mg/mL (7.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.2881 mL 36.4405 mL 72.8810 mL
5 mM 1.4576 mL 7.2881 mL 14.5762 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O / H2O 1 mM 7.2881 mL 36.4405 mL 72.8810 mL 182.2025 mL
5 mM 1.4576 mL 7.2881 mL 14.5762 mL 36.4405 mL
H2O / H2O 10 mM 0.7288 mL 3.6440 mL 7.2881 mL 18.2202 mL
15 mM 0.4859 mL 2.4294 mL 4.8587 mL 12.1468 mL
20 mM 0.3644 mL 1.8220 mL 3.6440 mL 9.1101 mL
25 mM 0.2915 mL 1.4576 mL 2.9152 mL 7.2881 mL
30 mM 0.2429 mL 1.2147 mL 2.4294 mL 6.0734 mL
40 mM 0.1822 mL 0.9110 mL 1.8220 mL 4.5551 mL
50 mM 0.1458 mL 0.7288 mL 1.4576 mL 3.6440 mL
60 mM 0.1215 mL 0.6073 mL 1.2147 mL 3.0367 mL
80 mM 0.0911 mL 0.4555 mL 0.9110 mL 2.2775 mL
100 mM 0.0729 mL 0.3644 mL 0.7288 mL 1.8220 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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6-Aminocaproic acid-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Aminocaproic acid-d61228656-08-3EACA-d6Epsilon-Amino-n-caproic acid-d66-Aminohexanoic acid-d6Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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