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  4. 6-Bromooxindole

6-Bromooxindole  (Synonyms: 6-Bromo-2-oxindole)

Cat. No.: HY-59227 Purity: 98.12%
Data Sheet
SDS
COA
Handling Instructions Technical Support

Solubility

In Vivo Dissolution Calculator

6-Bromo-2-oxindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

6-Bromooxindole Chemical Structure

6-Bromooxindole Chemical Structure

CAS No. : 99365-40-9

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Based on 1 publication(s) in Google Scholar

6-Bromooxindole Related Antibodies

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Description

6-Bromo-2-oxindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cellular Effect
Cell Line Type Value Description References
MDA-MB-231 IC50
74 μM
Compound: 26
Anticancer activity against human MDA-MB-231 cells assessed as cell growth incubated for 24 hrs by MTT assay
Anticancer activity against human MDA-MB-231 cells assessed as cell growth incubated for 24 hrs by MTT assay
[PMID: 36853972]
In Vitro

6-Bromo-2-oxindole is a secondary metabolite that has been isolated from the sea squirt (D. skoogi). It is cytotoxic to MDA-MB-231 breast cancer cells with an IC50 value of 74.41 μM. 6-Bromo-2-oxindole has been used in the synthesis of 1,3-disstituted 2-oxindoles and indolin-2-one p38α inhibitors, which have anti-inflammatory activity.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-Bromooxindole Related Antibodies
Molecular Weight

212.04

Formula

C8H6BrNO
CAS No.
Appearance

Solid

Color

Light yellow to light brown

SMILES

O=C1NC2=C(C=CC(Br)=C2)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (471.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7161 mL 23.5805 mL 47.1609 mL
5 mM 0.9432 mL 4.7161 mL 9.4322 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Purity & Documentation

Purity: 99.13%

Data Sheet (242 KB) SDS (393 KB)

COA (246 KB) HNMR (188 KB) RP-HPLC (248 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7161 mL 23.5805 mL 47.1609 mL 117.9023 mL
5 mM 0.9432 mL 4.7161 mL 9.4322 mL 23.5805 mL
10 mM 0.4716 mL 2.3580 mL 4.7161 mL 11.7902 mL
15 mM 0.3144 mL 1.5720 mL 3.1441 mL 7.8602 mL
20 mM 0.2358 mL 1.1790 mL 2.3580 mL 5.8951 mL
25 mM 0.1886 mL 0.9432 mL 1.8864 mL 4.7161 mL
30 mM 0.1572 mL 0.7860 mL 1.5720 mL 3.9301 mL
40 mM 0.1179 mL 0.5895 mL 1.1790 mL 2.9476 mL
50 mM 0.0943 mL 0.4716 mL 0.9432 mL 2.3580 mL
60 mM 0.0786 mL 0.3930 mL 0.7860 mL 1.9650 mL
80 mM 0.0590 mL 0.2948 mL 0.5895 mL 1.4738 mL
100 mM 0.0472 mL 0.2358 mL 0.4716 mL 1.1790 mL
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6-Bromooxindole Related Classifications

Keywords:

6-Bromooxindole99365-40-96-Bromo-2-oxindoleBiochemical Assay Reagentsbiochemical reagentbiological materialorganic compoundlife scienceInhibitorinhibitorinhibit

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