2. Epigenetics TGF-beta/Smad
  3. PKC
  4. 6-Deoxyisojacareubin

6-Deoxyisojacareubin is a PKC inhibitor that inhibits the proliferation of QGY-7703 cells in a concentration-dependent manner. 6-Deoxyisojacareubin is also a natural product that can be obtained from Garcinia nervosa. 6-Deoxyisojacareubin can be used in cancer research.

For research use only. We do not sell to patients.

6-Deoxyisojacareubin Chemical Structure

6-Deoxyisojacareubin Chemical Structure

CAS No. : 26486-92-0

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6-Deoxyisojacareubin Related Antibodies

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PKC PKCα PKCβ PKCγ PKCδ PKCε PKCη PKCζ PKCθ PKCμ PKC-ι ℩ PKCι

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Description

6-Deoxyisojacareubin is a PKC inhibitor that inhibits the proliferation of QGY-7703 cells in a concentration-dependent manner. 6-Deoxyisojacareubin is also a natural product that can be obtained from Garcinia nervosa. 6-Deoxyisojacareubin can be used in cancer research[1].

Cellular Effect
Cell Line Type Value Description References
SH-SY5Y EC50
5.1 μM
Compound: 19
Neuroprotective activity against 6-hydroxydopamine-induced human SH-SY5Y cell death after 24 hrs by MTT assay
Neuroprotective activity against 6-hydroxydopamine-induced human SH-SY5Y cell death after 24 hrs by MTT assay
[PMID: 25051453]
Molecular Weight

310.30

Formula

C18H14O5
CAS No.
SMILES

O=C1C2=C(OC3=C1C=CC=C3O)C(C=CC(C)(C)O4)=C4C=C2O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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6-Deoxyisojacareubin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Deoxyisojacareubin26486-92-0PKCProtein kinase CGarcinia nervosacancerQGY-7703Inhibitorinhibitorinhibit

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