2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside

6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside 

Cat. No.: HY-152695
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6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside Chemical Structure

6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside Chemical Structure

CAS No. : 2072145-35-6

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6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside Related Antibodies

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Description

6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cellular Effect
Cell Line Type Value Description References
MRC5 EC50
> 64 μM
Compound: 14
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 3 days by resazurin dye based fluorimetric analysis
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 3 days by resazurin dye based fluorimetric analysis
[PMID: 33667845]
Molecular Weight

284.24

Formula

C11H13FN4O4
CAS No.
SMILES

F[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(OC)=NC=N3)O[C@@H]1CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside2072145-35-6Nucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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