6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid

Cat. No.: HY-N9199 Purity: ≥96.0%: FAQs
Data Sheet SDS COA Handling Instructions

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6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid (Compound 14) is an osteoclast inhibitor with anti-osteoclastogenic activity. 6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid can be obtained from Eriobotrya japonica leaves. 6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid can be used in osteoporosis research.

For research use only. We do not sell to patients.

6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid Chemical Structure

CAS No. : 194027-11-7

Size	Price	Stock	Quantity
500 μg	USD 300	In-stock	Estimated Time of Arrival: December 31
1 mg	USD 490	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Description

Molecular Weight

486.68

Formula

C₃₀H₄₆O₅

CAS No.

194027-11-7

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12C([C@@]3([H])[C@@](CC2)(CC[C@H]([C@]3(O)C)C)C(O)=O)=CC[C@@]4([H])[C@]1(C[C@@H]([C@]5([H])[C@@]4(CCC(C5(C)C)=O)C)O)C

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 24.34 mg/mL (50.01 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0547 mL	10.2737 mL	20.5474 mL
5 mM	0.4109 mL	2.0547 mL	4.1095 mL
10 mM	0.2055 mL	1.0274 mL	2.0547 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥96.0%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (255 KB)

Handling Instructions (2659 KB)

References

[1]. Tan H, et al. A structure-activity relationship study on antiosteoclastogenesis effect of triterpenoids from the leaves of loquat (Eriobotrya japonica). Phytomedicine. 2015 Apr 15;22(4):498-503. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0547 mL	10.2737 mL	20.5474 mL	51.3685 mL
	5 mM	0.4109 mL	2.0547 mL	4.1095 mL	10.2737 mL
	10 mM	0.2055 mL	1.0274 mL	2.0547 mL	5.1368 mL
	15 mM	0.1370 mL	0.6849 mL	1.3698 mL	3.4246 mL
	20 mM	0.1027 mL	0.5137 mL	1.0274 mL	2.5684 mL
	25 mM	0.0822 mL	0.4109 mL	0.8219 mL	2.0547 mL
	30 mM	0.0685 mL	0.3425 mL	0.6849 mL	1.7123 mL
	40 mM	0.0514 mL	0.2568 mL	0.5137 mL	1.2842 mL
	50 mM	0.0411 mL	0.2055 mL	0.4109 mL	1.0274 mL