2. Natural Products
  3. Plants Phenols
  4. Leguminosae Monophenols
  5. Gleditsia sinensis Lam.
  6. (7R,8S)-Dehydrodiconiferyl alcohol

(7R,8S)-Dehydrodiconiferyl alcohol is a natural product that can be isolated from the thorns of Gleditsia sinensis. (7R,8S)-Dehydrodiconiferyl alcohol shows antitumor activity.

For research use only. We do not sell to patients.

(7R,8S)-Dehydrodiconiferyl alcohol Chemical Structure

(7R,8S)-Dehydrodiconiferyl alcohol Chemical Structure

CAS No. : 155836-29-6

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(7R,8S)-Dehydrodiconiferyl alcohol Related Antibodies

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Description

(7R,8S)-Dehydrodiconiferyl alcohol is a natural product that can be isolated from the thorns of Gleditsia sinensis. (7R,8S)-Dehydrodiconiferyl alcohol shows antitumor activity[1].

Cellular Effect
Cell Line Type Value Description References
Hep 3B2 IC50
54.6 μM
Compound: 2b
Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay
[PMID: 29567344]
HepG2 IC50
104.4 μM
Compound: 2b
Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
[PMID: 29567344]
RAW264.7 IC50
8.5 μM
Compound: 7
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells preincubated with compound for 1 hr before exposure to LPS measured after 24 hrs by Griess reaction method
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells preincubated with compound for 1 hr before exposure to LPS measured after 24 hrs by Griess reaction method
[PMID: 21435874]
In Vitro

(7R,8S)-Dehydrodiconiferyl alcohol shows cytotoxic effect on human ovarian cancer (SKOV-3) cells with an IC50 of 48.86 ± 9.11 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(7R,8S)-Dehydrodiconiferyl alcohol Related Antibodies
Molecular Weight

358.39

Formula

C20H22O6
CAS No.
SMILES

OC[C@@H]1C2=C(C(OC)=CC(/C=C/CO)=C2)O[C@H]1C3=CC(OC)=C(O)C=C3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(7R,8S)-Dehydrodiconiferyl alcohol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(7R,8S)-Dehydrodiconiferyl alcohol155836-29-6OthersGleditsia sinensisSKOV-3antitumor activityovarian cancerInhibitorinhibitorinhibit

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