1. Vitamin D Related/Nuclear Receptor
  2. Estrogen Receptor/ERR
  3. Dehydrodiconiferyl alcohol

Dehydrodiconiferyl alcohol is an estrogen receptor agonist that can promote BMP-2-induced osteoblastogenesis. Dehydrodiconiferyl alcohol also exerts anti-inflammatory activity through inactivation of NF-κB pathways.

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Dehydrodiconiferyl alcohol Chemical Structure

Dehydrodiconiferyl alcohol Chemical Structure

CAS No. : 4263-87-0

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Description

Dehydrodiconiferyl alcohol is an estrogen receptor agonist that can promote BMP-2-induced osteoblastogenesis. Dehydrodiconiferyl alcohol also exerts anti-inflammatory activity through inactivation of NF-κB pathways[1][2].

Cellular Effect
Cell Line Type Value Description References
Hep 3B2 IC50
65.5 μM
Compound: 2
Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay
[PMID: 29567344]
HepG2 IC50
78.6 μM
Compound: 2
Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
[PMID: 29567344]
Molecular Weight

358.39

Formula

C20H22O6

CAS No.
SMILES

OC1=CC=C(C2OC3=C(C2CO)C=C(/C=C/CO)C=C3OC)C=C1OC

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Dehydrodiconiferyl alcohol
Cat. No.:
HY-N2682B
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