2. Cell Cycle/DNA Damage Others
  3. Biochemical Assay Reagents DNA/RNA Synthesis
  4. 8-Bromoadenine

8-Bromoadenine  (Synonyms: 8-Bromo-9H-purin-6-amine)

Cat. No.: HY-W076740
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8-Bromoadenine (8-Bromo-9H-purin-6-amine) is a DNA radiosensitizer that inhibits DNA single-strand break repair in cells. 8-Bromoadenine is a brominated derivative of adenine, and radioactive adenine can be prepared by replacing bromine with deuterium.

For research use only. We do not sell to patients.

8-Bromoadenine Chemical Structure

8-Bromoadenine Chemical Structure

CAS No. : 6974-78-3

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8-Bromoadenine Related Antibodies

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Description

8-Bromoadenine (8-Bromo-9H-purin-6-amine) is a DNA radiosensitizer that inhibits DNA single-strand break repair in cells. 8-Bromoadenine is a brominated derivative of adenine, and radioactive adenine can be prepared by replacing bromine with deuterium[1][2].

In Vitro

8-Bromoadenine (0.1 mM; 30-90 min) inhibits DNA single-strand break repair in HeLa-M cell monolayer cultures. And after γ irradiation, the quality of DNA synthesized by cells is lower than that of DNA synthesized by cells without purine addition[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

8-Bromoadenine Related Antibodies
Molecular Weight

214.02

Formula

C5H4BrN5
CAS No.
Appearance

Solid

SMILES

BrC1=NC2=C(N1)C(N)=NC=N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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8-Bromoadenine Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

8-Bromoadenine6974-78-38-Bromo-9H-purin-6-amineBiochemical Assay ReagentsDNA/RNA SynthesisInhibitorinhibitorinhibit

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