2. Stem Cell/Wnt TGF-beta/Smad
  3. PKA
  4. 8-MA-cAMP

8-MA-cAMP (8-Methylamino-cAMP) is a cyclic AMP analog that acts as a site-selective PKA agonist with similar affinity for the B site of type I and type II protein kinase A. 8-MA-cAMP is used in conjunction with priming analogs that show site A preference, such as 8-piperidinyl cAMP, to achieve selective stimulation of type I.

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8-MA-cAMP Chemical Structure

8-MA-cAMP Chemical Structure

CAS No. : 33823-18-6

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8-MA-cAMP Related Antibodies

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Description

8-MA-cAMP (8-Methylamino-cAMP) is a cyclic AMP analog that acts as a site-selective PKA agonist with similar affinity for the B site of type I and type II protein kinase A. 8-MA-cAMP is used in conjunction with priming analogs that show site A preference, such as 8-piperidinyl cAMP, to achieve selective stimulation of type I[1].

Molecular Weight

358.25

Formula

C11H15N6O6P
CAS No.
SMILES

O[C@@H]1[C@H](OP2(O)=O)[C@@H](CO2)O[C@H]1N3C(NC)=NC4=C3N=CN=C4N
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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8-MA-cAMP Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

8-MA-cAMP33823-18-68-Methylamino-cAMPPKAProtein kinase AAnaloguesselective agonistcAMPInhibitorinhibitorinhibit

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