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  4. 9-Deazaguanine

9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP).

For research use only. We do not sell to patients.

9-Deazaguanine Chemical Structure

9-Deazaguanine Chemical Structure

CAS No. : 65996-58-9

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Based on 1 publication(s) in Google Scholar

9-Deazaguanine Related Antibodies

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1 Publications Citing Use of MCE 9-Deazaguanine

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Description

9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP)[1].

Molecular Weight

150.14

Formula

C6H6N4O
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

NC(NC1=O)=NC2=C1NC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 3.33 mg/mL (22.18 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.6604 mL 33.3022 mL 66.6045 mL
5 mM 1.3321 mL 6.6605 mL 13.3209 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.18%

COA (250 KB) HNMR (122 KB) RP-HPLC (193 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.6605 mL 33.3023 mL 66.6045 mL 166.5113 mL
5 mM 1.3321 mL 6.6605 mL 13.3209 mL 33.3023 mL
10 mM 0.6660 mL 3.3302 mL 6.6605 mL 16.6511 mL
15 mM 0.4440 mL 2.2202 mL 4.4403 mL 11.1008 mL
20 mM 0.3330 mL 1.6651 mL 3.3302 mL 8.3256 mL
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9-Deazaguanine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

9-Deazaguanine65996-58-9OthersInhibitorinhibitorinhibit

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