2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. 9-Deazaguanine

9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP).

For research use only. We do not sell to patients.

9-Deazaguanine Chemical Structure

9-Deazaguanine Chemical Structure

CAS No. : 65996-58-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Based on 1 publication(s) in Google Scholar

9-Deazaguanine Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE 9-Deazaguanine

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  • References

  • Customer Review

Description

9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP)[1].

Molecular Weight

150.14

Formula

C6H6N4O
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

NC(NC1=O)=NC2=C1NC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 3.33 mg/mL (22.18 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.6604 mL 33.3020 mL 66.6041 mL
5 mM 1.3321 mL 6.6604 mL 13.3208 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.18%

SDS (770 KB)

COA (250 KB) HNMR (122 KB) RP-HPLC (193 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.6604 mL 33.3020 mL 66.6041 mL 166.5101 mL
5 mM 1.3321 mL 6.6604 mL 13.3208 mL 33.3020 mL
10 mM 0.6660 mL 3.3302 mL 6.6604 mL 16.6510 mL
15 mM 0.4440 mL 2.2201 mL 4.4403 mL 11.1007 mL
20 mM 0.3330 mL 1.6651 mL 3.3302 mL 8.3255 mL
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9-Deazaguanine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

9-Deazaguanine65996-58-9DNA/RNA SynthesisInhibitorinhibitorinhibit

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