9(S)-HODE-¹³C₁₈  (Synonyms: (+)-α-Dimophecolic acid-¹³C₁₈)

9(S)-HODE-¹³C₁₈ ((+)-α-Dimophecolic acid-¹³C₁₈) is ¹³C labeled 9S-HODE. 9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO^[1][2].

314.31

¹³C₁₈H₃₂O₃

73543-67-6

O[13C]([13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13C@@H](/[13CH]=[13CH]/[13CH]=[13CH]\[13CH2][13CH2][13CH2][13CH2][13CH3])O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Liu S, et al. Linoleic acid derivatives target miR-361-3p/BTG2 to confer anticancer effects in acute myeloid leukemia. J Biochem Mol Toxicol. 2023 Nov;37(11):e23481.  [Content Brief]

  [3]. Spiteller P, et al. 9-Hydroxy-10, 12-octadecadienoic acid (9-HODE) and 13-hydroxy-9, 11-octadecadienoic acid (13-HODE): excellent markers for lipid peroxidation[J]. Chemistry and Physics of Lipids, 1997, 89(2): 131-139.