2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. Alizapride

Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive disorders.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Alizapride hydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Alizapride Chemical Structure

Alizapride Chemical Structure

CAS No. : 59338-93-1

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Alizapride Related Antibodies

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Description

Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive disorders[1][3].

IC50 & Target

Dopamine 2 receptor
In Vivo

Alizapride (2.5, 5, 10, 25 μg/kg; SC; 7 consecutive days) significantly reduces the bound IgG-sensitized erythrocytes with Splenic macrophages isolated from animals[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Duncan–Hartley guinea pigs[2]
Dosage: 2.5, 5, 10, 25 μg/kg
Administration: Alizapride (2.5, 5, 10, 25 μg/kg; SC; 7 consecutive days)
Result: Reduced the clearance of IgG-sensitized RBCs.
Molecular Weight

315.37

Formula

C16H21N5O2
CAS No.
SMILES

O=C(C1=C(OC)C=C(NN=N2)C2=C1)NCC3N(CC=C)CCC3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Alizapride Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alizapride59338-93-1Dopamine Receptorantiemetic,dopamine receptor antagonistInhibitorinhibitorinhibit

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