2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Alosetron-d3 hydrochloride

Alosetron-d3 hydrochloride  (Synonyms: GR-68755C d3)

Cat. No.: HY-70050CS Purity: ≥99.0%
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Alosetron-d3 (hydrochloride) is deuterium labeled Alosetron, which is a serotonin 5HT3-receptor antagonist.

For research use only. We do not sell to patients.

Alosetron-d<sub>3</sub> hydrochloride Chemical Structure

Alosetron-d3 hydrochloride Chemical Structure

CAS No. : 1189919-71-8

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1 mg USD 280 In-stock
5 mg USD 850 In-stock
10 mg USD 1400 In-stock
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Other Forms of Alosetron-d3 hydrochloride:

Alosetron-d3 hydrochloride Related Antibodies

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Description

Alosetron-d3 (hydrochloride) is deuterium labeled Alosetron, which is a serotonin 5HT3-receptor antagonist.

Molecular Weight

333.83

Formula

C17H16D3ClN4O
CAS No.
Unlabeled CAS

122852-69-1
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1N(CC2=C(C)N=CN2)CCC3=C1C4=CC=CC=C4N3C([2H])([2H])[2H].[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 33.33 mg/mL (99.84 mM; Need ultrasonic)

H2O : 33.33 mg/mL (99.84 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9955 mL 14.9777 mL 29.9554 mL
5 mM 0.5991 mL 2.9955 mL 5.9911 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 2.9955 mL 14.9777 mL 29.9554 mL 74.8884 mL
5 mM 0.5991 mL 2.9955 mL 5.9911 mL 14.9777 mL
10 mM 0.2996 mL 1.4978 mL 2.9955 mL 7.4888 mL
15 mM 0.1997 mL 0.9985 mL 1.9970 mL 4.9926 mL
20 mM 0.1498 mL 0.7489 mL 1.4978 mL 3.7444 mL
25 mM 0.1198 mL 0.5991 mL 1.1982 mL 2.9955 mL
30 mM 0.0999 mL 0.4993 mL 0.9985 mL 2.4963 mL
40 mM 0.0749 mL 0.3744 mL 0.7489 mL 1.8722 mL
50 mM 0.0599 mL 0.2996 mL 0.5991 mL 1.4978 mL
60 mM 0.0499 mL 0.2496 mL 0.4993 mL 1.2481 mL
80 mM 0.0374 mL 0.1872 mL 0.3744 mL 0.9361 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Alosetron-d3 hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alosetron-d31189919-71-8GR-68755C d35-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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