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  6. Antennapedia Peptide

Antennapedia Peptide  (Synonyms: Penetratin peptide)

Cat. No.: HY-P0307 Purity: 98.35%
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Antennapedia Peptide (Penetratin peptide) is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides.

For research use only. We do not sell to patients.

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Antennapedia Peptide Chemical Structure

Antennapedia Peptide Chemical Structure

CAS No. : 188842-14-0

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Based on 1 publication(s) in Google Scholar

Other Forms of Antennapedia Peptide:

Antennapedia Peptide Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Antennapedia Peptide (Penetratin peptide) is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides.

In Vitro

Antennapedia (Antp)-SMCC-cytochrome c conjugate (5 μg/mL) activates caspase-dependent apoptosis of HeLa cells. The Antp-SMCC-cytochrome c conjugate reduces the clonogenic survival of Hela cells, and inhibits clonogenic survival[1]. ANTP-SmacN7 fusion protein can transduce and accumulate in cells, while SmacN7 alone cannot. ANTP-SmacN7 fusion proteins have a radiation-sensitising effect on EC109 cells. ANTP-SmacN7 combined with radiation does not promote further increases in caspase-3 protein expression, it increases the levels of cleaved caspase-3[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antennapedia Peptide Related Antibodies
Molecular Weight

2246.73

Formula

C104H168N34O20S
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys
Sequence Shortening

RQIKIWFQNRRMKWKK
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (44.51 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4451 mL 2.2255 mL 4.4509 mL
5 mM 0.0890 mL 0.4451 mL 0.8902 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.4451 mL 2.2255 mL 4.4509 mL 11.1273 mL
5 mM 0.0890 mL 0.4451 mL 0.8902 mL 2.2255 mL
10 mM 0.0445 mL 0.2225 mL 0.4451 mL 1.1127 mL
15 mM 0.0297 mL 0.1484 mL 0.2967 mL 0.7418 mL
20 mM 0.0223 mL 0.1113 mL 0.2225 mL 0.5564 mL
25 mM 0.0178 mL 0.0890 mL 0.1780 mL 0.4451 mL
30 mM 0.0148 mL 0.0742 mL 0.1484 mL 0.3709 mL
40 mM 0.0111 mL 0.0556 mL 0.1113 mL 0.2782 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Antennapedia Peptide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antennapedia Peptide188842-14-0Penetratin peptideOthersInhibitorinhibitorinhibit

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