1. GPCR/G Protein
  2. Endothelin Receptor
  3. Atrial Natriuretic Peptide (ANP) (1-28), rat

Atrial Natriuretic Peptide (ANP) (1-28), rat  (Synonyms: Atrial natriuretic factor (1-28) (rat))

Cat. No.: HY-P1236 Purity: 96.37%
COA Handling Instructions

Atrial Natriuretic Peptide (ANP) (1-28), rat is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.

For research use only. We do not sell to patients.

Atrial Natriuretic Peptide (ANP) (1-28), rat Chemical Structure

Atrial Natriuretic Peptide (ANP) (1-28), rat Chemical Structure

CAS No. : 88898-17-3

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500 μg USD 180 In-stock
1 mg USD 280 In-stock
5 mg USD 980 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Atrial Natriuretic Peptide (ANP) (1-28), rat:

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Description

Atrial Natriuretic Peptide (ANP) (1-28), rat is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.

IC50 & Target

Endothelin-1[1]

In Vitro

Rat ANP (1-28) and rat BNP-45, which are the respective major circulating forms of ANP and BNP in rats, potently inhibited Ang II-stimulated endothelin-1 secretion in a concentration-dependent manner. Rat ANP (5-25) is less effective that Rat ANP(1-28) with respect to inhibiting immunoreactive (ir)-endothelin-1 secretion and increasing cellular cyclic GMP. Rat ANP (1-28) inhibits the secretion of ir-endothelin-1 in a concentration-dependent manner between 0.01 and 1 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

3062.41

Formula

C128H205N45O39S2

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge: Cys7-Cys23)

Sequence Shortening

SLRRSSCFGGRIDRIGAQSGLGCNSFRY (Disulfide bridge: Cys7-Cys23)

SMILES

[SLRRSSCFGGRIDRIGAQSGLGCNSFRY (Disulfide bridge: Cys7-Cys23)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Atrial Natriuretic Peptide (ANP) (1-28), rat
Cat. No.:
HY-P1236
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