2. Neuronal Signaling
  3. Beta-secretase
  4. BACE-1 inhibitor 1

BACE-1 inhibitor 1 (Compound 8a) is a potent BACE-1 inhibitor with an IC50 of 56 nM.

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BACE-1 inhibitor 1 Chemical Structure

BACE-1 inhibitor 1 Chemical Structure

CAS No. : 1262858-14-9

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BACE-1 inhibitor 1 Related Antibodies

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Description

BACE-1 inhibitor 1 (Compound 8a) is a potent BACE-1 inhibitor with an IC50 of 56 nM[1].

IC50 & Target

IC50: 56 nM (BACE-1)[1]
Molecular Weight

443.22

Formula

C17H14BrF3N4O2
CAS No.
SMILES

BrC1=CC=C(C(NC2=CC=C(F)C([C@@]3(C(F)F)N=C(N)COC3)=C2)=O)N=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BACE-1 inhibitor 1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BACE-1 inhibitor 11262858-14-9Beta-secretaseBACEβ-SecretaseInhibitorinhibitorinhibit

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BACE-1 inhibitor 1
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HY-112297
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