1. Signaling Pathways
  2. Neuronal Signaling
  3. Beta-secretase
  4. Beta-secretase Inhibitors

Beta-secretase Inhibitors

BACE1

BACE2

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Beta-secretase Inhibitors
Product Name BACE1 BACE2 Purity
Se-Methylselenocysteine
BACE1
  ≥98.0%
Verubecestat
BACE1
BACE2
99.56%
Epiberberine chloride
BACE1
  99.02%
LY2886721
BACE1
  99.74%
BCA
BACE1, IC50: 28 μM
BACE1, Ki: 43 μM
  99.76%
Lanabecestat
BACE1
  99.67%
BACE2-IN-1
BACE1, Ki: 815.1 nM
BACE2, Ki: 1.6 nM
99.4%
LY2811376
BACE1
  99.89%
Atabecestat
BACE1
  99.77%
Scoulerine
BACE1
  99.27%
BACE1-IN-1
BACE1
  99.02%
AZD3839 free base
BACE1
  99.91%
(1α,1'S,4β)-Lanabecestat
BACE1
 
LX2343
BACE1, IC50: 11.43 μM
  99.80%
Epiberberine
BACE1
  98.46%
Sophoflavescenol
BACE1
  98.15%
BACE1-IN-5
BACE1
 
BACE1-IN-2
BACE1
 
BACE1-IN-4
BACE1
 
AM-6494
BACE1
 
AMG-8718
BACE1, IC50: 0.0007 μM
BACE2, IC50: 0.005 μM
AChE/BACE1/GSK3β-IN-1
BACE1, IC50: 20 μM
 
BACE1-IN-10
BACE1
 
AChE/BChE-IN-12
BACE1, IC50: 10.65 ± 0. μM
 
Memoquin
BACE1, IC50: 108 nM
 
Aloeresin D
BACE1
  99.69%
BACE1-IN-14
BACE1, EC50: 0.7 μM
BACE2, EC50: 1.6 μM
BACE1-IN-11
BACE1, IC50: 72 μM
 
β-Secretase Inhibitor III
BACE1
 
OM99-2
BACE1
 
BACE1-IN-9
BACE1
 
TB-11
BACE1, IC50: 48.8 nM