2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Bethanechol

Bethanechol  (Synonyms: Carbamyl-β-methylcholine)

Cat. No.: HY-B0406
Handling Instructions

Molarity Calculator

Bethanechol (Carbamyl-β-methylcholine), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Bethanechol chloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Bethanechol Chemical Structure

Bethanechol Chemical Structure

CAS No. : 674-38-4

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Other In-stock Forms of Bethanechol:

Other Forms of Bethanechol:

Bethanechol Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Bethanechol

View All mAChR Isoform Specific Products:

View All Isoforms
mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

  • Biological Activity

  • Purity & Documentation

  • References

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Description

Bethanechol (Carbamyl-β-methylcholine), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system[1].

IC50 & Target

mAChR1

 

mAChR3

 

mAChR4

 

mAChR5

 

In Vitro

Bethanechol (0.3-300 μM) significantly reduces ileal pacemaker potentials[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bethanechol Related Antibodies
In Vivo

Bethanechol (2-12 mg/kg; i.p.) induces drinking and increased urine output of rats in a dose-dependent fashion[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female rats of the Blue Spruce Farms (Sprague-Dawley) (280-330 g) [4]
Dosage: 2 mg/kg, 4 mg/kg, 8 mg/kg, 12 mg/kg
Administration: Intraperitoneal injection
Result: Increased water intake during the first hr in a dose-dependent fashion up to the highest dose administered (12 mg/kg).
Clinical Trial
Molecular Weight

161.22

Formula

C7H17N2O2
CAS No.
SMILES

CC(OC(N)=O)C[N+](C)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Bethanechol Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bethanechol674-38-4Carbamyl-β-methylcholinemAChRMuscarinic acetylcholine receptorparasympathomimeticparasympatheticreceptorspostoperativeurinaryretentionpostpartumurinary ,retentionoverflowincontinenceInhibitorinhibitorinhibit

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