Bisoctrizole 

Bisoctrizole is a broad-spectrum UV absorber that absorbs UVB and UVA rays while reflecting and scattering UV rays.

658.87

C₄₁H₅₀N₆O₂

103597-45-1

Solid

White to off-white

OC1=C(N2N=C3C(C=CC=C3)=N2)C=C(C(C)(C)CC(C)(C)C)C=C1CC4=CC(C(C)(C)CC(C)(C)C)=CC(N5N=C6C(C=CC=C6)=N5)=C4O

Room temperature in continental US; may vary elsewhere.

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

• [1]. Herzog B, et al. In vivo and in vitro assessment of UVA protection by sunscreen formulations containing either butyl methoxy dibenzoyl methane, methylene bis-benzotriazolyl tetramethylbutylphenol, or microfine ZnO. Int J Cosmet Sci. 2002 Jun;24(3):170-85.  [Content Brief]

  [2]. Mavon A, et al. In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacol Physiol. 2007;20(1):10-20.  [Content Brief]

  [3]. Ashby J, et al. Lack of binding to isolated estrogen or androgen receptors, and inactivity in the immature rat uterotrophic assay, of the ultraviolet sunscreen filters Tinosorb M-active and Tinosorb S. Regul Toxicol Pharmacol. 2001 Dec;34(3):287-91.  [Content Brief]