2. Metabolic Enzyme/Protease
  3. Lipoxygenase
  4. CMI977

CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor.

For research use only. We do not sell to patients.

CMI977 Chemical Structure

CMI977 Chemical Structure

CAS No. : 175212-04-1

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CMI977 Related Antibodies

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Description

CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor.

IC50 & Target

5-LO

 

In Vitro

CMI977 is a potent 5-lipoxygenase (5-LO) inhibitor that intervenes in the production of leukotrienes and is presently being developed for the treatment of chronic asthma. It is a single enantiomer with an all-trans (2S,5S) configuration. Of the four isomers of CMI977, the S,S isomer is found to have the best biological activity and is selected for further development.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CMI977 Related Antibodies
Molecular Weight

322.33

Formula

C16H19FN2O4
CAS No.
SMILES

O=C(N)N(CCC#C[C@H]1O[C@H](COC2=CC=C(F)C=C2)CC1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CMI977 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CMI977175212-04-1LDP977CMI 977CMI-977LDP 977LDP-977LipoxygenaseLOXInhibitorinhibitorinhibit

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