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  4. DL-threo-2-methylisocitrate

DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1(ICL1).

For research use only. We do not sell to patients.

DL-threo-2-methylisocitrate Chemical Structure

DL-threo-2-methylisocitrate Chemical Structure

CAS No. : 71183-66-9

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DL-threo-2-methylisocitrate Related Antibodies

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Description

DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1(ICL1). IC50 value: Target: The Km of purified recombinant ICL1 for threo-D(s)L(s)-isocitrate (ICA) was determined to be 188 μM using Michaelis-Menten non-linear least squares fit, with a kcat of 5.24 s-1. The Km for DL-threo-2-methylisocitrate (MICA) was approximately fourfold higher at 718 μM with a kcat of 1.25 s-1.

Molecular Weight

206.15

Formula

C7H10O7
CAS No.
SMILES

O[C@@](C)(C(O)=O)[C@@]([H])(C(O)=O)CC(O)=O.O[C@](C)(C(O)=O)[C@]([H])(C(O)=O)CC(O)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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DL-threo-2-methylisocitrate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DL-threo-2-methylisocitrate71183-66-9OthersInhibitorinhibitorinhibit

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