2. Metabolic Enzyme/Protease Autophagy
  3. HMG-CoA Reductase (HMGCR) Autophagy
  4. Fluvastatin-d6 sodium

Fluvastatin-d6 sodium  (Synonyms: XU 62-320-d6)

Cat. No.: HY-14664AS Purity: 98.98%
COA Handling Instructions

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Fluvastatin-d6 (sodium) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.

For research use only. We do not sell to patients.

Fluvastatin-d<sub>6</sub> sodium Chemical Structure

Fluvastatin-d6 sodium Chemical Structure

Size Price Stock Quantity
1 mg USD 450 In-stock
5 mg USD 1280 In-stock
10 mg USD 2050 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Fluvastatin-d6 sodium Related Antibodies

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Description

Fluvastatin-d6 (sodium) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.

Clinical Trial
Molecular Weight

439.48

Formula

C24H19D6FNNaO4
Unlabeled CAS

93957-55-2
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C([O-])C[C@H](O)C[C@H](O)/C=C/C(N1C(C([2H])([2H])[2H])C([2H])([2H])[2H])=C(C2=CC=C(F)C=C2)C3=C1C=CC=C3.[Na+]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (113.77 mM; Need ultrasonic)

H2O : 50 mg/mL (113.77 mM; Need ultrasonic)

DMSO : 50 mg/mL (113.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 50 mg/mL (113.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2754 mL 11.3771 mL 22.7542 mL
5 mM 0.4551 mL 2.2754 mL 4.5508 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O / DMSO / DMSO 1 mM 2.2754 mL 11.3771 mL 22.7542 mL 56.8854 mL
5 mM 0.4551 mL 2.2754 mL 4.5508 mL 11.3771 mL
10 mM 0.2275 mL 1.1377 mL 2.2754 mL 5.6885 mL
15 mM 0.1517 mL 0.7585 mL 1.5169 mL 3.7924 mL
20 mM 0.1138 mL 0.5689 mL 1.1377 mL 2.8443 mL
25 mM 0.0910 mL 0.4551 mL 0.9102 mL 2.2754 mL
30 mM 0.0758 mL 0.3792 mL 0.7585 mL 1.8962 mL
40 mM 0.0569 mL 0.2844 mL 0.5689 mL 1.4221 mL
50 mM 0.0455 mL 0.2275 mL 0.4551 mL 1.1377 mL
60 mM 0.0379 mL 0.1896 mL 0.3792 mL 0.9481 mL
80 mM 0.0284 mL 0.1422 mL 0.2844 mL 0.7111 mL
100 mM 0.0228 mL 0.1138 mL 0.2275 mL 0.5689 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Fluvastatin-d6 sodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fluvastatin-d6XU 62-320-d6HMG-CoA Reductase (HMGCR)AutophagyHMG-CoAreductasevascularsmoothmuscleoxidativestressNrf2-dependentantioxidantpathwayInhibitorinhibitorinhibit

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