2. Metabolic Enzyme/Protease Anti-infection
  3. HIV Integrase HIV
  4. HIV-1 integrase inhibitor 3

HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM.

For research use only. We do not sell to patients.

HIV-1 integrase inhibitor 3 Chemical Structure

HIV-1 integrase inhibitor 3 Chemical Structure

CAS No. : 1638504-56-9

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HIV-1 integrase inhibitor 3 Related Antibodies

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Description

HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM.

IC50 & Target

IC50: 2.7 nM (INST)[1]
Cellular Effect
Cell Line Type Value Description References
HOS CC50
> 250 μM
Compound: 6'b
Cytotoxicity against HOS cells assessed as reduction in cell viability after 48 hrs by ATPLite luminescence assay
Cytotoxicity against HOS cells assessed as reduction in cell viability after 48 hrs by ATPLite luminescence assay
[PMID: 28737946]
In Vitro

HIV-1 integrase inhibitor 3 (compound 4c) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. HIV-1 integrase inhibitor 3 also displays an antiviral inhibitory potency against the Q148H/G140S mutant with an EC50 of 7 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HIV-1 integrase inhibitor 3 Related Antibodies
Molecular Weight

432.42

Formula

C21H22F2N4O4
CAS No.
SMILES

NC(C1=CC(CCCCCO)=CN=C1N2O)=C(C(NCC3=CC=C(F)C=C3F)=O)C2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HIV-1 integrase inhibitor 3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HIV-1 integrase inhibitor 31638504-56-9HIV IntegraseHIVHuman immunodeficiency virusInhibitorinhibitorinhibit

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HIV-1 integrase inhibitor 3
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HY-108817
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