2. Immunology/Inflammation
  3. Interleukin Related
  4. IL-17A antagonist 3

IL-17A antagonist 3 is an IL-17A antagonist, compound 3.

For research use only. We do not sell to patients.

IL-17A antagonist 3 Chemical Structure

IL-17A antagonist 3 Chemical Structure

CAS No. : 2230780-65-9

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Based on 1 publication(s) in Google Scholar

IL-17A antagonist 3 Related Antibodies

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

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Description

IL-17A antagonist 3 is an IL-17A antagonist, compound 3[1].

IC50 & Target[1]

IL-17A

 

Molecular Weight

613.11

Formula

C33H33ClN6O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@@H](NC(C1=CC=NN1C)=O)CC2=CC(C3=CC(CCC4=O)=CC=C3)=CC=C2Cl)NC5=CC=C(C[C@@H](N4)C(NC)=O)C=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 6.67 mg/mL (10.88 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6310 mL 8.1551 mL 16.3103 mL
5 mM 0.3262 mL 1.6310 mL 3.2621 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6310 mL 8.1551 mL 16.3103 mL 40.7757 mL
5 mM 0.3262 mL 1.6310 mL 3.2621 mL 8.1551 mL
10 mM 0.1631 mL 0.8155 mL 1.6310 mL 4.0776 mL
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IL-17A antagonist 3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IL-17A antagonist 32230780-65-9Interleukin RelatedILInhibitorinhibitorinhibit

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