2. GPCR/G Protein
  3. Angiotensin Receptor
  4. Irbesartan-d4

Irbesartan-d4  (Synonyms: SR-47436-d4; BMS-186295-d4)

Cat. No.: HY-B0202S Purity: 99.46%
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Irbesartan-d4 is the deuterium labeled Irbesartan, which is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist.

For research use only. We do not sell to patients.

Irbesartan-d<sub>4</sub> Chemical Structure

Irbesartan-d4 Chemical Structure

CAS No. : 1216883-23-6

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1 mg USD 350 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Irbesartan-d4:

Irbesartan-d4 Related Antibodies

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Description

Irbesartan-d4 is the deuterium labeled Irbesartan, which is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist.

Molecular Weight

432.55

Formula

C25H24D4N6O
CAS No.
Unlabeled CAS

138402-11-6
Appearance

Solid

Color

White to off-white

SMILES

O=C1N(CC2=C([2H])C([2H])=C(C3=C(C4=NN=NN4)C=CC=C3)C([2H])=C2[2H])C(CCCC)=NC15CCCC5
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (231.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 20 mg/mL (46.24 mM)

DMSO : ≥ 14 mg/mL (32.37 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : ≥ 0.5 mg/mL (1.16 mM)

Ethanol : ≥ 0.5 mg/mL (1.16 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3119 mL 11.5594 mL 23.1187 mL
5 mM 0.4624 mL 2.3119 mL 4.6237 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / Ethanol / DMSO / DMF / DMSO 1 mM 2.3119 mL 11.5594 mL 23.1187 mL 57.7968 mL
DMSO / DMF / DMSO 5 mM 0.4624 mL 2.3119 mL 4.6237 mL 11.5594 mL
10 mM 0.2312 mL 1.1559 mL 2.3119 mL 5.7797 mL
15 mM 0.1541 mL 0.7706 mL 1.5412 mL 3.8531 mL
20 mM 0.1156 mL 0.5780 mL 1.1559 mL 2.8898 mL
25 mM 0.0925 mL 0.4624 mL 0.9247 mL 2.3119 mL
30 mM 0.0771 mL 0.3853 mL 0.7706 mL 1.9266 mL
DMF / DMSO 40 mM 0.0578 mL 0.2890 mL 0.5780 mL 1.4449 mL
DMSO 50 mM 0.0462 mL 0.2312 mL 0.4624 mL 1.1559 mL
60 mM 0.0385 mL 0.1927 mL 0.3853 mL 0.9633 mL
80 mM 0.0289 mL 0.1445 mL 0.2890 mL 0.7225 mL
100 mM 0.0231 mL 0.1156 mL 0.2312 mL 0.5780 mL
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Irbesartan-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Irbesartan-d41216883-23-6SR-47436-d4 BMS-186295-d4Angiotensin ReceptorInhibitorinhibitorinhibit

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