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  3. Biochemical Assay Reagents
  4. Luciferase

Luciferase is an enzyme that catalyzes the oxidation of the substrate luciferin and produces bioluminescence. Luciferase can reflect the content of related substances by detecting the intensity of the light signal. Luciferase can monitor the growth and metastasis of cancer cells and evaluate the efficacy of anticancer agents.

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Luciferase Chemical Structure

Luciferase Chemical Structure

CAS No. : 9014-00-0

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Based on 1 publication(s) in Google Scholar

Other Forms of Luciferase:

Luciferase Related Antibodies

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Description

Luciferase is an enzyme that catalyzes the oxidation of the substrate luciferin and produces bioluminescence. Luciferase can reflect the content of related substances by detecting the intensity of the light signal. Luciferase can monitor the growth and metastasis of cancer cells and evaluate the efficacy of anticancer agents[1][2][3].

In Vitro

Luciferase monitors changes in ATP concentration in different regions within HL-1 cells and outside the cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Luciferase Related Antibodies
In Vivo

Luciferase (labels HEK293 cells stably expressing pmeLUC；i.p. or intramass injection) can measure the ATP concentration in the tumor microenvironment in real-time in the mouse tumor model inoculated with HEK293 cells stably expressing pmeLUC[1].
Luciferase can clearly monitor the growth of cancer cells in a mouse model in which RENCALUC cells are inoculated subcutaneously[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

[Luciferase]
Structure Classification
Initial Source

Neonothopanus nambi fungus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O : 20 mg/mL (Need ultrasonic)

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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

SDS (251 KB)

COA (229 KB)

Handling Instructions (2659 KB)
References
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Luciferase Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Luciferase9014-00-0Biochemical Assay ReagentsHL-1cancer cellbioluminescenceInhibitorinhibitorinhibit

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