2. Anti-infection
  3. Bacterial Antibiotic
  4. Mafenide hydrochloride

Mafenide hydrochloride is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis.

For research use only. We do not sell to patients.

Mafenide hydrochloride Chemical Structure

Mafenide hydrochloride Chemical Structure

CAS No. : 138-37-4

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100 mg USD 84 In-stock
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Other Forms of Mafenide hydrochloride:

Mafenide hydrochloride Related Antibodies

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Description

Mafenide hydrochloride is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis[1][2].

Clinical Trial
Molecular Weight

222.69

Formula

C7H11ClN2O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=C(CN)C=C1)(N)=O.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (561.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4905 mL 22.4527 mL 44.9055 mL
5 mM 0.8981 mL 4.4905 mL 8.9811 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4905 mL 22.4527 mL 44.9055 mL 112.2637 mL
5 mM 0.8981 mL 4.4905 mL 8.9811 mL 22.4527 mL
10 mM 0.4491 mL 2.2453 mL 4.4905 mL 11.2264 mL
15 mM 0.2994 mL 1.4968 mL 2.9937 mL 7.4842 mL
20 mM 0.2245 mL 1.1226 mL 2.2453 mL 5.6132 mL
25 mM 0.1796 mL 0.8981 mL 1.7962 mL 4.4905 mL
30 mM 0.1497 mL 0.7484 mL 1.4968 mL 3.7421 mL
40 mM 0.1123 mL 0.5613 mL 1.1226 mL 2.8066 mL
50 mM 0.0898 mL 0.4491 mL 0.8981 mL 2.2453 mL
60 mM 0.0748 mL 0.3742 mL 0.7484 mL 1.8711 mL
80 mM 0.0561 mL 0.2807 mL 0.5613 mL 1.4033 mL
100 mM 0.0449 mL 0.2245 mL 0.4491 mL 1.1226 mL
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Mafenide hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mafenide138-37-4BacterialAntibioticInhibitorinhibitorinhibit

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