Methicillin

Cat. No.: HY-121544: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Methicillin is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins.Methicillin can be used for the research of skin infections, osteomyelitis, and endocarditis.

For research use only. We do not sell to patients.

Methicillin Chemical Structure

CAS No. : 61-32-5

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Other In-stock Forms of Methicillin:

Methicillin sodium salt

Other Forms of Methicillin:

Methicillin sodium salt In-stock
Methicillin sodium hydrate Get quote

4 Publications Citing Use of MCE Methicillin

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

β-lactam

In Vitro

Methicillin (20 μg/mL, 24 h) results in a rapid decrease in CFU of S. aureus^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Methicillin (Intramuscular administration, 40 mg/kg every 6 h, 5 days), in S. aureus.-infected rabbits^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

380.42

Formula

C₁₇H₂₀N₂O₆S

CAS No.

61-32-5

SMILES

OC([C@@H]1N(C2=O)[C@@](SC(C)1C)([H])[C@@H]2NC(C(C(OC)=CC=C3)=C3OC)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sharon S. Castle. Methicillin. xPharm: The Comprehensive Pharmacology Reference 2007, Pages 1-4.

[2]. Jaime Carrizosa, et al. Treatment of Experimental Staphylococcus aureus Endocarditis: Comparison of Cephalothin, Cefazolin, and Methicillin. Antimicrob Agents Chemother. 1978 Jan; 13(1): 74–77.

Methicillin Related Classifications

Infection

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methicillin61-32-5Penicillin-binding protein (PBP)BacterialAntibioticHistamine Receptorβ-lactam antibioticpenicillin-binding proteinskin infectionsStaphylococcus epidermidisMRSA.Inhibitorinhibitorinhibit

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